Mechanism of La Crosse virus inhibition by ribavirin

L. F. Cassidy, J. L. Patterson

    Research output: Contribution to journalArticlepeer-review

    45 Scopus citations


    The effect of ribavirin on the growth and replication of La Crosse virus was examined. The data suggest that low concentrations of ribavirin have a marked effect on the initial steps of La Crosse virus transcription. The therapeutic potential of ribvirin in the treatment of human California encephalitis serotype infections is discussed in light of these findings.

    Original languageEnglish (US)
    Pages (from-to)2009-2011
    Number of pages3
    JournalAntimicrobial agents and chemotherapy
    Issue number11
    StatePublished - 1989

    ASJC Scopus subject areas

    • Pharmacology
    • Pharmacology (medical)
    • Infectious Diseases


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