Abstract
In 1951, McArdle described a glycogen storage disorder which presents primarily as a myopathy. It is characterized by muscle pain, weakness and exercise intolerance with elevated creatine kinase from rhabdomyolysis. The pathophysiology involves a deficiency of myophosphorylase enzyme resulting in an inability to degrade glycogen stores. We present a novel case of McArdle disease (glycogen storage disease V [GSDV]) in a patient who had sickle cell trait and bulimia. The disease went unrecognized despite several admissions to the hospital with increased creatine kinase and muscle myopathy until the patient's initial presentation with acute renal failure.
Original language | English (US) |
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Pages (from-to) | 313-316 |
Number of pages | 4 |
Journal | Southern medical journal |
Volume | 100 |
Issue number | 3 |
DOIs | |
State | Published - Mar 1 2007 |
Externally published | Yes |
Keywords
- Bulimia
- Glycogen storage disease V
- GSDV
- McArdle disease
- Sickle cell trait
ASJC Scopus subject areas
- Medicine(all)