TY - JOUR
T1 - Maximal postextrasystolic potentiation following multiple extrasystoles
T2 - A simple means of myocardial assessment
AU - Cragg, Andrew
AU - Einzig, Stanley
AU - Rholl, Kenneth
AU - Rysavy, Joseph
AU - Castaneda, Wilfrido
AU - Amplatz, Kurt
PY - 1983
Y1 - 1983
N2 - To obtain consistent, reproducible postextrasytolic potentiation (PESP), a single closely coupled extrasystole (ES) must be introduced using tranvenous pacing. We hypothesized that multiple ES (spontaneous or catheter induced) produce maximal PESP at all coupling intervals (CI). Differences in PESP between single and double ES were assessed in dogs at varying CI by two different methods [systolic time intervals‐PEP/LVET, and endocardial markers‐ejection fraction (EF)]. Single ES produced variable decreases in PEP/LVET (−8.6 ± 2.7% (SE) to −22.9 ± 4.0%) depending on the CI duration. Double ES produced maximal decreases (−26.0 ± 1.2%) at all CI. A similar relationship was noted for EF following single ES (8.6 ± 2.7% to 43.0 ± 4.0%) and double ES (42.9 ± 1.3%). Double ES produced maximal PESP at all CI. This finding may allow simple myocardial assessment during routine left ventricular catheterization without simultaneous right ventricular catheterization.
AB - To obtain consistent, reproducible postextrasytolic potentiation (PESP), a single closely coupled extrasystole (ES) must be introduced using tranvenous pacing. We hypothesized that multiple ES (spontaneous or catheter induced) produce maximal PESP at all coupling intervals (CI). Differences in PESP between single and double ES were assessed in dogs at varying CI by two different methods [systolic time intervals‐PEP/LVET, and endocardial markers‐ejection fraction (EF)]. Single ES produced variable decreases in PEP/LVET (−8.6 ± 2.7% (SE) to −22.9 ± 4.0%) depending on the CI duration. Double ES produced maximal decreases (−26.0 ± 1.2%) at all CI. A similar relationship was noted for EF following single ES (8.6 ± 2.7% to 43.0 ± 4.0%) and double ES (42.9 ± 1.3%). Double ES produced maximal PESP at all CI. This finding may allow simple myocardial assessment during routine left ventricular catheterization without simultaneous right ventricular catheterization.
KW - coronary artery surgery
KW - coronary heart disease
KW - left ventricular function
KW - postextrasystolic potentiation
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U2 - 10.1002/ccd.1810090304
DO - 10.1002/ccd.1810090304
M3 - Article
C2 - 6192930
AN - SCOPUS:0020576664
SN - 1522-1946
VL - 9
SP - 251
EP - 260
JO - Catheterization and Cardiovascular Interventions
JF - Catheterization and Cardiovascular Interventions
IS - 3
ER -