TY - JOUR
T1 - Maternal vitamin D status has no effect on the ontogeny of calcium-binding proteins in the duodenum, kidney and cerebellum of fetal mice
AU - Shamley, D. R.
AU - Buffenstein, R.
AU - Veale, G.
AU - Pettifor, J. M.
PY - 1993
Y1 - 1993
N2 - The effects of vitamin D3 deficiency on the ontogeny of calcium-binding proteins (CaBPs) and the vitamin D receptor in the duodenum, kidney and cerebellum of the mouse were examined. Maternal vitamin D status did not affect the time of appearance of the fetal 28 kDa CaBP (CaBP-D(28k)) in the cerebellum, kidney and duodenum, and the 9 kDa CaBP (CaBP-D(9k)) in the intestine and kidney. Vitamin D receptor was undetectable in all fetal tissues, regardless of maternal vitamin D status, at all stages of gestation examined. Thus it appears that maternal vitamin D status does not affect the ontogeny of CaBP-D(9k) or CaBP-D(28k) in the mouse fetus. The factors that influence the appearance of calbindins in the fetus are unclear.
AB - The effects of vitamin D3 deficiency on the ontogeny of calcium-binding proteins (CaBPs) and the vitamin D receptor in the duodenum, kidney and cerebellum of the mouse were examined. Maternal vitamin D status did not affect the time of appearance of the fetal 28 kDa CaBP (CaBP-D(28k)) in the cerebellum, kidney and duodenum, and the 9 kDa CaBP (CaBP-D(9k)) in the intestine and kidney. Vitamin D receptor was undetectable in all fetal tissues, regardless of maternal vitamin D status, at all stages of gestation examined. Thus it appears that maternal vitamin D status does not affect the ontogeny of CaBP-D(9k) or CaBP-D(28k) in the mouse fetus. The factors that influence the appearance of calbindins in the fetus are unclear.
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U2 - 10.1677/joe.0.1390473
DO - 10.1677/joe.0.1390473
M3 - Article
C2 - 8133214
AN - SCOPUS:0027715722
VL - 139
SP - 473
EP - 478
JO - Journal of Endocrinology
JF - Journal of Endocrinology
SN - 0022-0795
IS - 3
ER -