Massive upper gastrointestinal hemorrhage due to invasive hepatocellular carcinoma and hepato-gastric fistula

Hari Sayana, Osama Yousef, Wendell K. Clarkston

Research output: Contribution to journalArticlepeer-review

13 Scopus citations

Abstract

A 36-year-old male Asian immigrant with a history of hepatitis B and hepatitis C related unresectable hepatocellular carcinoma in the left lobe of the liver presented with hematemesis and severe anemia. He was diagnosed with a liver mass that was resected 8 years ago described as a benign tumor in his home country. He had received trans-arterial chemoembolization (TACE) four months ago after subsequent diagnosis of unresectable hepatoma, and currently was receiving chemotherapy with Sorafenib. After resuscitation, a contrast enhanced computerized tomography was performed which showed fistulization of hepatocellular carcinoma into adjacent stomach. This finding was confirmed during endoscopy with direct visualization of the fistulous opening. Hepatocellular carcinoma (HCC) invading the gastrointestinal (GI) tract is rare. We present a case and literature review of HCC with local invasion of the stomach causing massive upper GI bleeding after receiving TACE.

Original languageEnglish (US)
Pages (from-to)7472-7475
Number of pages4
JournalWorld Journal of Gastroenterology
Volume19
Issue number42
DOIs
StatePublished - Nov 14 2013
Externally publishedYes

Keywords

  • Fistula
  • Hepatocellular carcinoma
  • Hepatogastric fistula
  • Upper gastrointestinal bleeding

ASJC Scopus subject areas

  • Gastroenterology

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