TY - JOUR
T1 - Massive upper gastrointestinal hemorrhage due to invasive hepatocellular carcinoma and hepato-gastric fistula
AU - Sayana, Hari
AU - Yousef, Osama
AU - Clarkston, Wendell K.
PY - 2013/11/14
Y1 - 2013/11/14
N2 - A 36-year-old male Asian immigrant with a history of hepatitis B and hepatitis C related unresectable hepatocellular carcinoma in the left lobe of the liver presented with hematemesis and severe anemia. He was diagnosed with a liver mass that was resected 8 years ago described as a benign tumor in his home country. He had received trans-arterial chemoembolization (TACE) four months ago after subsequent diagnosis of unresectable hepatoma, and currently was receiving chemotherapy with Sorafenib. After resuscitation, a contrast enhanced computerized tomography was performed which showed fistulization of hepatocellular carcinoma into adjacent stomach. This finding was confirmed during endoscopy with direct visualization of the fistulous opening. Hepatocellular carcinoma (HCC) invading the gastrointestinal (GI) tract is rare. We present a case and literature review of HCC with local invasion of the stomach causing massive upper GI bleeding after receiving TACE.
AB - A 36-year-old male Asian immigrant with a history of hepatitis B and hepatitis C related unresectable hepatocellular carcinoma in the left lobe of the liver presented with hematemesis and severe anemia. He was diagnosed with a liver mass that was resected 8 years ago described as a benign tumor in his home country. He had received trans-arterial chemoembolization (TACE) four months ago after subsequent diagnosis of unresectable hepatoma, and currently was receiving chemotherapy with Sorafenib. After resuscitation, a contrast enhanced computerized tomography was performed which showed fistulization of hepatocellular carcinoma into adjacent stomach. This finding was confirmed during endoscopy with direct visualization of the fistulous opening. Hepatocellular carcinoma (HCC) invading the gastrointestinal (GI) tract is rare. We present a case and literature review of HCC with local invasion of the stomach causing massive upper GI bleeding after receiving TACE.
KW - Fistula
KW - Hepatocellular carcinoma
KW - Hepatogastric fistula
KW - Upper gastrointestinal bleeding
UR - http://www.scopus.com/inward/record.url?scp=84887573842&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84887573842&partnerID=8YFLogxK
U2 - 10.3748/wjg.v19.i42.7472
DO - 10.3748/wjg.v19.i42.7472
M3 - Article
C2 - 24259980
AN - SCOPUS:84887573842
SN - 1007-9327
VL - 19
SP - 7472
EP - 7475
JO - World Journal of Gastroenterology
JF - World Journal of Gastroenterology
IS - 42
ER -