Massive Transfusion in Adults:Diagnoses, Survival and Blood Bank Support

P. R. Sawyer, C. R. Harrison

Research output: Contribution to journalArticlepeer-review

28 Scopus citations


Abstract. In a retrospective study covering a 2‐year period (1986–1987), 125 patients received massive blood transfusion. Trauma accounted for only 29% of the cases. The larger nontrauma diagnostic categories were: gastrointestinal hemorrhage, 31%; cardiovascular surgery, 12%, and oncology cases, 9%. The overall survival rate was 60%; survival rates ranged from 38% for patients with hepatic failure to 100% for obstetric cases. Clinically important alloantibodies were present in 4%, and transfusion reactions occurred in 9%. Massive transfusions accounted for a significant proportion of total blood component usage: at least 12% of the yearly total red cell units, 20% of plasma, and 14% of platelets transfused.

Original languageEnglish (US)
Pages (from-to)199-203
Number of pages5
JournalVox Sanguinis
Issue number3
StatePublished - Apr 1990

ASJC Scopus subject areas

  • Hematology


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