Marijuana in Orthopaedics: Effects on Bone Health, Wound-Healing, Surgical Complications, and Pain Management

David M. Heath, Ezekial J. Koslosky, Katherine C. Bartush, Grant D. Hogue

Research output: Contribution to journalReview articlepeer-review

14 Scopus citations

Abstract

»Marijuana use is on the rise in the United States, and there is a paucity of information on the effects of cannabis and its chemical constituents on bone health, wound-healing, surgical complications, and pain management.»Current evidence suggests that cannabidiol (CBD) may enhance bone health and metabolism, while Δ9-tetrahydrocannabinol (Δ9-THC), the major psychoactive component in marijuana, has an inhibitory effect.»Marijuana users are at higher risk for delayed bone-healing, demonstrate lower bone mineral density, are at increased risk for fracture, and may experience postoperative complications such as increased opioid use and hyperemesis.

Original languageEnglish (US)
Article numbere21.00184
JournalJBJS Reviews
Volume10
Issue number2
DOIs
StatePublished - Feb 21 2022

ASJC Scopus subject areas

  • Surgery
  • Orthopedics and Sports Medicine

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