Management of pleural effusions in children with malignant lymphoma

John B. Pietsch, James A. Whitlock, Connie Ford, Marsha C. Kinney

Research output: Contribution to journalArticlepeer-review

22 Scopus citations


Purpose: The aim of this study was to determine potential problems in the diagnosis and management of children with pleural effusions and malignant lymphoma as well as the efficacy of thoracentesis. Methods: The case histories of six children with malignant lymphoma who presented with pleural effusions were reviewed. Thoracentesis was performed using the Seldinger technique. Results: Four of the children presented with symptoms and chest radiograph findings similar to pneumonia. A large mediastinal mass was present in two children. Pleural fluid analysis resulted in a definitive diagnosis of lymphoma in five of the six children. Two of the children had symptoms of reexpansion pulmonary edema after removal of pleural fluid. An empyema developed in one child after thoracotomy and chest tube placement. Reaccumulation of pleural fluid was common before initiating chemotherapy. Conclusions: Malignant pleural effusions frequently are present in children with non-Hodgkin's lymphoma. They may present with respiratory distress because of the size of the effusion, the mediastinal mass, or both. Management of these pleural effusions is associated with potential complications, some of which are life threatening. Thoracentesis is the initial diagnostic and therapeutic procedure of choice. The use of a Seldinger technique for thoracentesis has proved useful and safe. In patients with large effusions, aggressive removal of the pleural fluid may be followed by reexpansion pulmonary edema.

Original languageEnglish (US)
Pages (from-to)635-638
Number of pages4
JournalJournal of pediatric surgery
Issue number4
StatePublished - Apr 1999
Externally publishedYes


  • Lymphoma
  • Mediastinal mass
  • Pleural effusion
  • Pulmonary edema
  • Thoracentesis

ASJC Scopus subject areas

  • Surgery
  • Pediatrics, Perinatology, and Child Health


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