Management of calciphylaxis in a burn center: A case series and review of the literature

David N. Dado, Benjamin Huang, Daniel V. Foster, Jamison S. Nielsen, Jennifer M. Gurney, Benjamin D. Morrow, Kumar Sharma, Kevin K. Chung, Craig R. Ainsworth

Research output: Contribution to journalArticle

1 Scopus citations

Abstract

Calciphylaxis is a rare, necrotizing skin disorder usually associated with kidney disease, but also caused by many other systemic illnesses. This disease is associated with mortality rates as high as 80% at 1 year. We present the demographic and clinical data of nine patients with calciphylaxis treated at our burn center over a 10 year period. We review the literature on the clinical presentation, pathophysiology, diagnosis and treatment of this rare disease. We propose that these patients be treated similar to patients with thermal burn injury; meaning intensive wound care, surgical management, critical care and physical therapy. Burn centers are uniquely capable of caring for these incredibly complex patients due to their experience in managing patients with extensive skin and soft tissue defects, wounds and diseases.

Original languageEnglish (US)
Pages (from-to)241-246
Number of pages6
JournalBurns
Volume45
Issue number1
DOIs
StatePublished - Feb 2019

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Keywords

  • Calciphylaxis
  • Calficific uremic arteriolopathy

ASJC Scopus subject areas

  • Surgery
  • Emergency Medicine
  • Critical Care and Intensive Care Medicine

Cite this

Dado, D. N., Huang, B., Foster, D. V., Nielsen, J. S., Gurney, J. M., Morrow, B. D., Sharma, K., Chung, K. K., & Ainsworth, C. R. (2019). Management of calciphylaxis in a burn center: A case series and review of the literature. Burns, 45(1), 241-246. https://doi.org/10.1016/j.burns.2018.09.008