Management of calciphylaxis in a burn center

A case series and review of the literature

David N. Dado, Benjamin Huang, Daniel V. Foster, Jamison S. Nielsen, Jennifer M. Gurney, Benjamin D. Morrow, Kumar Sharma, Kevin K. Chung, Craig R. Ainsworth

Research output: Contribution to journalArticle

Abstract

Calciphylaxis is a rare, necrotizing skin disorder usually associated with kidney disease, but also caused by many other systemic illnesses. This disease is associated with mortality rates as high as 80% at 1 year. We present the demographic and clinical data of nine patients with calciphylaxis treated at our burn center over a 10 year period. We review the literature on the clinical presentation, pathophysiology, diagnosis and treatment of this rare disease. We propose that these patients be treated similar to patients with thermal burn injury; meaning intensive wound care, surgical management, critical care and physical therapy. Burn centers are uniquely capable of caring for these incredibly complex patients due to their experience in managing patients with extensive skin and soft tissue defects, wounds and diseases.

Original languageEnglish (US)
JournalBurns
DOIs
StateAccepted/In press - Jan 1 2018

Fingerprint

Calciphylaxis
Burn Units
Critical Care
Wounds and Injuries
Skin
Kidney Diseases
Rare Diseases
Hot Temperature
Demography
Mortality
Therapeutics

ASJC Scopus subject areas

  • Surgery
  • Emergency Medicine
  • Critical Care and Intensive Care Medicine

Cite this

Dado, D. N., Huang, B., Foster, D. V., Nielsen, J. S., Gurney, J. M., Morrow, B. D., ... Ainsworth, C. R. (Accepted/In press). Management of calciphylaxis in a burn center: A case series and review of the literature. Burns. https://doi.org/10.1016/j.burns.2018.09.008

Management of calciphylaxis in a burn center : A case series and review of the literature. / Dado, David N.; Huang, Benjamin; Foster, Daniel V.; Nielsen, Jamison S.; Gurney, Jennifer M.; Morrow, Benjamin D.; Sharma, Kumar; Chung, Kevin K.; Ainsworth, Craig R.

In: Burns, 01.01.2018.

Research output: Contribution to journalArticle

Dado, DN, Huang, B, Foster, DV, Nielsen, JS, Gurney, JM, Morrow, BD, Sharma, K, Chung, KK & Ainsworth, CR 2018, 'Management of calciphylaxis in a burn center: A case series and review of the literature', Burns. https://doi.org/10.1016/j.burns.2018.09.008
Dado, David N. ; Huang, Benjamin ; Foster, Daniel V. ; Nielsen, Jamison S. ; Gurney, Jennifer M. ; Morrow, Benjamin D. ; Sharma, Kumar ; Chung, Kevin K. ; Ainsworth, Craig R. / Management of calciphylaxis in a burn center : A case series and review of the literature. In: Burns. 2018.
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