Magnetic resonance imaging mapping of brain function: Human visual cortex

J. W. Belliveau, K. K. Kwong, D. N. Kennedy, J. R. Baker, C. E. Stern, R. Benson, D. A. Chesler, R. M. Weisskoff, M. S. Cohen, R. B.H. Tootell, P. T. Fox, T. J. Brady, B. R. Rosen

Research output: Contribution to journalArticlepeer-review

124 Scopus citations

Abstract

Magnetic resonance imaging (MRI) studies of human brain activity are described. Task-induced changes in brain cognitive state were measured using high-speed MRI techniques sensitive to changes in cerebral blood volume (CBV), blood flow (CBF), and blood oxygenation. These techniques were used to generate the first functional MRI maps of human task activation, by using a visual stimulus paradigm. The methodology of MRI brain mapping and results from the investigation of the functional organization and frequency response of human primary visual cortex (V1) are presented.

Original languageEnglish (US)
Pages (from-to)S59-S65
JournalInvestigative Radiology
Volume27
Issue numberSUPPL. 2
DOIs
StatePublished - 1992
Externally publishedYes

Keywords

  • brain function
  • cerebral blood flow
  • magnetic resonance imaging

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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