Magnesium sulfate as a tocolytic agent

Patrick S. Ramsey, Dwight J. Rouse

Research output: Contribution to journalArticlepeer-review

25 Scopus citations


Although magnesium sulfate is widely used as a tocolytic agent in the hope of preventing spontaneous preterm birth, there is a paucity of data from large well-designed randomized clinical studies demonstrating the efficacy of magnesium sulfate therapy. Given the potential for untoward side effects and the inherent risks of magnesium sulfate therapy, a thorough understanding of the potential risks and benefits of this agent is needed. To accomplish this understanding we have provided a detailed review the history, pharmacology, physiology, maternal/fetal side effects, and tocolytic efficacy of magnesium sulfate.

Original languageEnglish (US)
Pages (from-to)236-247
Number of pages12
JournalSeminars in Perinatology
Issue number4
StatePublished - Jan 1 2001
Externally publishedYes

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Obstetrics and Gynecology


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