Lymphangitic spread of hepatocellular carcinoma.

D. Kimberley Molina, Philip T. Valente

Research output: Contribution to journalArticlepeer-review

6 Scopus citations


Pulmonary lymphangitic carcinomatosis is a well-documented phenomenon caused by spread of carcinoma to the pulmonary vasculature and lymphatics, often resulting in respiratory failure and cor pulmonale. It has been described in numerous types of carcinoma, most commonly occurring with carcinomas of the breast and stomach and with choriocarcinoma. We report the case of a patient who presented with increasing shortness of breath and dyspnea on exertion. Autopsy findings revealed diffuse pulmonary vascular spread of a hepatocellular carcinoma to the lungs. To our knowledge, this is the first reported case of lymphangitic spread of a hepatocellular carcinoma causing respiratory compromise (lymphangitic carcinomatosis).

Original languageEnglish (US)
Pages (from-to)e11-13
JournalArchives of pathology & laboratory medicine
Issue number1
StatePublished - Jan 2003

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Medical Laboratory Technology


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