Lung transplant infection

Sergio R. Burguete, Diego J. Maselli, Juan F. Fernandez, Stephanie M Levine

Research output: Contribution to journalArticle

29 Citations (Scopus)

Abstract

Lung transplantation has become an accepted therapeutic procedure for the treatment of end-stage pulmonary parenchymal and vascular disease. Despite improved survival rates over the decades, lung transplant recipients have lower survival rates than other solid organ transplant recipients. The morbidity and mortality following lung transplantation is largely due to infection- and rejection-related complications. This article will review the common infections that develop in the lung transplant recipient, including the general risk factors for infection in this population, and the most frequent bacterial, viral, fungal and other less frequent opportunistic infections. The epidemiology, diagnosis, prophylaxis, treatment and outcomes for the different microbial pathogens will be reviewed. The effects of infection on lung transplant rejection will also be discussed.

Original languageEnglish (US)
Pages (from-to)22-38
Number of pages17
JournalRespirology
Volume18
Issue number1
DOIs
StatePublished - Jan 2013

Fingerprint

Transplants
Lung
Lung Transplantation
Infection
Survival Rate
Opportunistic Infections
Graft Rejection
Vascular Diseases
Lung Diseases
Epidemiology
Morbidity
Mortality
Therapeutics
Population
Transplant Recipients

Keywords

  • Aspergillus
  • bacterial pneumonia
  • cytomegalovirus
  • immunosuppression
  • lung transplantation

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine

Cite this

Burguete, S. R., Maselli, D. J., Fernandez, J. F., & Levine, S. M. (2013). Lung transplant infection. Respirology, 18(1), 22-38. https://doi.org/10.1111/j.1440-1843.2012.02196.x

Lung transplant infection. / Burguete, Sergio R.; Maselli, Diego J.; Fernandez, Juan F.; Levine, Stephanie M.

In: Respirology, Vol. 18, No. 1, 01.2013, p. 22-38.

Research output: Contribution to journalArticle

Burguete, SR, Maselli, DJ, Fernandez, JF & Levine, SM 2013, 'Lung transplant infection', Respirology, vol. 18, no. 1, pp. 22-38. https://doi.org/10.1111/j.1440-1843.2012.02196.x
Burguete SR, Maselli DJ, Fernandez JF, Levine SM. Lung transplant infection. Respirology. 2013 Jan;18(1):22-38. https://doi.org/10.1111/j.1440-1843.2012.02196.x
Burguete, Sergio R. ; Maselli, Diego J. ; Fernandez, Juan F. ; Levine, Stephanie M. / Lung transplant infection. In: Respirology. 2013 ; Vol. 18, No. 1. pp. 22-38.
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