Low relapse rate leads to high concordance of sustained virologic response (SVR) at 12 weeks with SVR at 24 weeks after treatment with ABT-450/ritonavir, ombitasvir, and dasabuvir plus ribavirin in subjects with chronic hepatitis c virus genotype 1 infection in the AVIATOR study

Fred Poordad; Kosh Agarwal; Ziad Younes; Daniel Cohen; Wangang Xie; Thomas Podsadecki

doi:10.1093/cid/ciu865

Low relapse rate leads to high concordance of sustained virologic response (SVR) at 12 weeks with SVR at 24 weeks after treatment with ABT-450/ritonavir, ombitasvir, and dasabuvir plus ribavirin in subjects with chronic hepatitis c virus genotype 1 infection in the AVIATOR study

Fred Poordad
, Kosh Agarwal
, Ziad Younes
, Daniel Cohen
, Wangang Xie
, Thomas Podsadecki

Research output: Contribution to journal › Article › peer-review

22 Scopus citations

Abstract

In 247 subjects with hepatitis C virus genotype 1 infection treated with the interferon-free regimen of ABT-450/ritonavir, ombitasvir, and dasabuvir plus ribavirin, concordance of a sustained virologic response at 12 and 24 weeks supports the use of the earlier time point as a primary efficacy endpoint for trials of this interferon-free regimen.

Original language	English (US)
Pages (from-to)	608-610
Number of pages	3
Journal	Clinical Infectious Diseases
Volume	60
Issue number	4
DOIs	https://doi.org/10.1093/cid/ciu865
State	Published - Feb 15 2015

Keywords

concordance
direct-acting antivirals
hepatitis C
sustained virologic response

ASJC Scopus subject areas

Microbiology (medical)
Infectious Diseases

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Poordad, F., Agarwal, K., Younes, Z., Cohen, D., Xie, W., & Podsadecki, T. (2015). Low relapse rate leads to high concordance of sustained virologic response (SVR) at 12 weeks with SVR at 24 weeks after treatment with ABT-450/ritonavir, ombitasvir, and dasabuvir plus ribavirin in subjects with chronic hepatitis c virus genotype 1 infection in the AVIATOR study. Clinical Infectious Diseases, 60(4), 608-610. https://doi.org/10.1093/cid/ciu865

Low relapse rate leads to high concordance of sustained virologic response (SVR) at 12 weeks with SVR at 24 weeks after treatment with ABT-450/ritonavir, ombitasvir, and dasabuvir plus ribavirin in subjects with chronic hepatitis c virus genotype 1 infection in the AVIATOR study. / Poordad, Fred; Agarwal, Kosh; Younes, Ziad et al.
In: Clinical Infectious Diseases, Vol. 60, No. 4, 15.02.2015, p. 608-610.

Research output: Contribution to journal › Article › peer-review

Poordad, F, Agarwal, K, Younes, Z, Cohen, D, Xie, W & Podsadecki, T 2015, 'Low relapse rate leads to high concordance of sustained virologic response (SVR) at 12 weeks with SVR at 24 weeks after treatment with ABT-450/ritonavir, ombitasvir, and dasabuvir plus ribavirin in subjects with chronic hepatitis c virus genotype 1 infection in the AVIATOR study', Clinical Infectious Diseases, vol. 60, no. 4, pp. 608-610. https://doi.org/10.1093/cid/ciu865

Poordad F, Agarwal K, Younes Z, Cohen D, Xie W, Podsadecki T. Low relapse rate leads to high concordance of sustained virologic response (SVR) at 12 weeks with SVR at 24 weeks after treatment with ABT-450/ritonavir, ombitasvir, and dasabuvir plus ribavirin in subjects with chronic hepatitis c virus genotype 1 infection in the AVIATOR study. Clinical Infectious Diseases. 2015 Feb 15;60(4):608-610. doi: 10.1093/cid/ciu865

Poordad, Fred ; Agarwal, Kosh ; Younes, Ziad et al. / Low relapse rate leads to high concordance of sustained virologic response (SVR) at 12 weeks with SVR at 24 weeks after treatment with ABT-450/ritonavir, ombitasvir, and dasabuvir plus ribavirin in subjects with chronic hepatitis c virus genotype 1 infection in the AVIATOR study. In: Clinical Infectious Diseases. 2015 ; Vol. 60, No. 4. pp. 608-610.

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Low relapse rate leads to high concordance of sustained virologic response (SVR) at 12 weeks with SVR at 24 weeks after treatment with ABT-450/ritonavir, ombitasvir, and dasabuvir plus ribavirin in subjects with chronic hepatitis c virus genotype 1 infection in the AVIATOR study

Abstract

Keywords

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