Low-dose inhalational nitric oxide in persistent pulmonary hypertension of the newborn

J. P. Kinsella; S. R. Neish; E. Shaffer; S. H. Abman

doi:10.1016/0140-6736(92)92687-B

Low-dose inhalational nitric oxide in persistent pulmonary hypertension of the newborn

J. P. Kinsella, S. R. Neish, E. Shaffer, S. H. Abman

Research output: Contribution to journal › Article › peer-review

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Abstract

We studied the effects of inhaled nitric oxide (NO) in 9 newborn infants with severe persistent pulmonary hypertension (PPHN) who were candidates for extracorporeal membrane oxygenation treatment. With low doses of NO (10-20 ppm) all showed rapid improvement in oxygenation without reduction of systemic blood pressure. In 6 infants treated with inhaled NO for 24 h, clinical improvement was sustained at 6 ppm.

Original language	English (US)
Pages (from-to)	819-820
Number of pages	2
Journal	The Lancet
Volume	340
Issue number	8823
DOIs	https://doi.org/10.1016/0140-6736(92)92687-B
State	Published - Oct 3 1992
Externally published	Yes

ASJC Scopus subject areas

Medicine(all)

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10.1016/0140-6736(92)92687-B

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