TY - JOUR
T1 - Longitudinal computational fluid dynamics study of aneurysmal dilatation in a chronic DeBakey type III aortic dissection
AU - Karmonik, Christof
AU - Partovi, Sasan
AU - Müller-Eschner, Matthias
AU - Bismuth, Jean
AU - Davies, Mark G.
AU - Shah, Dipan J.
AU - Loebe, Matthias
AU - Böckler, Dittmar
AU - Lumsden, Alan B.
AU - Von Tengg-Kobligk, Hendrik
PY - 2012/7
Y1 - 2012/7
N2 - Computational fluid dynamics, which uses numeric methods and algorithms for the simulation of blood flow by solving the Navier-Stokes equations on computational meshes, is enhancing the understanding of disease progression in type III aortic dissections. To illustrate this, we examined the changes in patient-derived geometries of aortic dissections, which showed progressive false lumen aneurysmal dilatation (26% diameter increase) during follow-up. Total pressure was decreased by 29% during systole and by 34% during retrograde flow. At the site of the highest false lumen dilatation, the temporal average of total pressure decreased from 45 to 22 Pa, and maximal average wall shear stress decreased from 0.9 to 0.4 Pa. These first results in the study of disease progression of type III DeBakey aortic dissection with computational fluid dynamics are encouraging.
AB - Computational fluid dynamics, which uses numeric methods and algorithms for the simulation of blood flow by solving the Navier-Stokes equations on computational meshes, is enhancing the understanding of disease progression in type III aortic dissections. To illustrate this, we examined the changes in patient-derived geometries of aortic dissections, which showed progressive false lumen aneurysmal dilatation (26% diameter increase) during follow-up. Total pressure was decreased by 29% during systole and by 34% during retrograde flow. At the site of the highest false lumen dilatation, the temporal average of total pressure decreased from 45 to 22 Pa, and maximal average wall shear stress decreased from 0.9 to 0.4 Pa. These first results in the study of disease progression of type III DeBakey aortic dissection with computational fluid dynamics are encouraging.
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U2 - 10.1016/j.jvs.2012.02.064
DO - 10.1016/j.jvs.2012.02.064
M3 - Article
C2 - 22579075
AN - SCOPUS:84862990202
VL - 56
SP - 260-263.e1
JO - Journal of Vascular Surgery
JF - Journal of Vascular Surgery
SN - 0741-5214
IS - 1
ER -