Abstract
316L stainless steel (316L SS) has been extensively used for making orthopedic, dental and cardiovascular implants. The use of phosphonic acid self-assembled monolayers (SAMs) on 316L SS has been previously explored for potential biomedical applications. In this study, we have investigated the long-term stability of methyl (-CH3) and carboxylic acid (-COOH)-terminated phosphonic acid SAMs on 316L under physiological conditions. The stability of SAMs on mechanically polished and electropolished 316L SS was also investigated as a part of this study. Well-ordered and uniform -CH 3- and -COOH-terminated SAMs were coated on mechanically polished and electropolished 316L SS surfaces. The long-term stability of SAMs on 316L SS was investigated for up to 28 days in Tris-buffered saline (TBS) at 37 °C using x-ray photoelectron spectroscopy, atomic force microscopy and contact angle goniometry. A significant amount of phosphonic acid molecules was desorbed from the 316L SS surfaces within 1 to 7 days of TBS immersion followed by a slow desorption of molecules over the remaining days. The -COOH-terminated SAM was found to be more stable than the -CH3-terminated SAM on both mechanically and electropolished surfaces. No significant differences in the desorption behavior of SAMs were observed between mechanically and electropolished 316L SS surfaces.
| Original language | English (US) |
|---|---|
| Article number | 025008 |
| Journal | Biomedical Materials |
| Volume | 5 |
| Issue number | 2 |
| DOIs | |
| State | Published - 2010 |
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ASJC Scopus subject areas
- Chemistry (miscellaneous)
- Biochemistry
- Mechanics of Materials
- Medicine(all)
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Long-term stability of self-assembled monolayers on 316L stainless steel. / Kaufmann, C. R.; Mani, G.; Marton, D.; Johnson, D. M.; Agrawal, C. M.
In: Biomedical Materials, Vol. 5, No. 2, 025008, 2010.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Long-term stability of self-assembled monolayers on 316L stainless steel
AU - Kaufmann, C. R.
AU - Mani, G.
AU - Marton, D.
AU - Johnson, D. M.
AU - Agrawal, C. M.
PY - 2010
Y1 - 2010
N2 - 316L stainless steel (316L SS) has been extensively used for making orthopedic, dental and cardiovascular implants. The use of phosphonic acid self-assembled monolayers (SAMs) on 316L SS has been previously explored for potential biomedical applications. In this study, we have investigated the long-term stability of methyl (-CH3) and carboxylic acid (-COOH)-terminated phosphonic acid SAMs on 316L under physiological conditions. The stability of SAMs on mechanically polished and electropolished 316L SS was also investigated as a part of this study. Well-ordered and uniform -CH 3- and -COOH-terminated SAMs were coated on mechanically polished and electropolished 316L SS surfaces. The long-term stability of SAMs on 316L SS was investigated for up to 28 days in Tris-buffered saline (TBS) at 37 °C using x-ray photoelectron spectroscopy, atomic force microscopy and contact angle goniometry. A significant amount of phosphonic acid molecules was desorbed from the 316L SS surfaces within 1 to 7 days of TBS immersion followed by a slow desorption of molecules over the remaining days. The -COOH-terminated SAM was found to be more stable than the -CH3-terminated SAM on both mechanically and electropolished surfaces. No significant differences in the desorption behavior of SAMs were observed between mechanically and electropolished 316L SS surfaces.
AB - 316L stainless steel (316L SS) has been extensively used for making orthopedic, dental and cardiovascular implants. The use of phosphonic acid self-assembled monolayers (SAMs) on 316L SS has been previously explored for potential biomedical applications. In this study, we have investigated the long-term stability of methyl (-CH3) and carboxylic acid (-COOH)-terminated phosphonic acid SAMs on 316L under physiological conditions. The stability of SAMs on mechanically polished and electropolished 316L SS was also investigated as a part of this study. Well-ordered and uniform -CH 3- and -COOH-terminated SAMs were coated on mechanically polished and electropolished 316L SS surfaces. The long-term stability of SAMs on 316L SS was investigated for up to 28 days in Tris-buffered saline (TBS) at 37 °C using x-ray photoelectron spectroscopy, atomic force microscopy and contact angle goniometry. A significant amount of phosphonic acid molecules was desorbed from the 316L SS surfaces within 1 to 7 days of TBS immersion followed by a slow desorption of molecules over the remaining days. The -COOH-terminated SAM was found to be more stable than the -CH3-terminated SAM on both mechanically and electropolished surfaces. No significant differences in the desorption behavior of SAMs were observed between mechanically and electropolished 316L SS surfaces.
UR - http://www.scopus.com/inward/record.url?scp=77950228685&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=77950228685&partnerID=8YFLogxK
U2 - 10.1088/1748-6041/5/2/025008
DO - 10.1088/1748-6041/5/2/025008
M3 - Article
C2 - 20339168
AN - SCOPUS:77950228685
VL - 5
JO - Biomedical Materials (Bristol)
JF - Biomedical Materials (Bristol)
SN - 1748-6041
IS - 2
M1 - 025008
ER -