Localization of the hypothetical protein Cpn0797 in the cytoplasm of Chlamydia pneumoniae-infected host cells

Feng Dong, Rhonda Flores, Ding Chen, Jianhua Luo, Youmin Zhong, Zhongming Wu, Guangming Zhong

Research output: Contribution to journalArticle

16 Scopus citations

Abstract

Using antibodies raised with chlamydial fusion proteins, we have localized a protein encoded by the hypothetical open reading frame Cpn0797 in the cytoplasm of Chlamydia pneumoniae-infected host cells. The anti-Cpn0797 antibodies specifically recognized Cpn0797 protein without cross-reacting with either CPAFcp or CpnU796, the only two proteins known to be secreted into the host cell cytosol by C. pneumoniae organisms. Thus, Cpn0797 represents the third C. pneumoniae protein secreted into the host cell cytosol experimentally identified so far.

Original languageEnglish (US)
Pages (from-to)6479-6486
Number of pages8
JournalInfection and immunity
Volume74
Issue number11
DOIs
StatePublished - Nov 2006

ASJC Scopus subject areas

  • Parasitology
  • Microbiology
  • Immunology
  • Infectious Diseases

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