Localization of glucose-dependent insulinotropic polypeptide (GIP) to a gene cluster on chromosome 17q

T. B. Lewis; M. Saenz; P. O’Connell; R. J. Leach

doi:10.1006/geno.1994.1114

Localization of glucose-dependent insulinotropic polypeptide (GIP) to a gene cluster on chromosome 17q

T. B. Lewis, M. Saenz, P. O’Connell, R. J. Leach

Department of Cell Systems & Anatomy

Research output: Contribution to journal › Article › peer-review

6 Scopus citations

Abstract

Glucose-dependent insulinotropic polypeptide (GIP) has been regionally localized to a gene cluster on human chromosome 17q. Genetic mapping through CEPH reference families demonstrated that GIP was tightly linked to NME1 and PPY and fully linked to HOXB6 and NGFR. High-resolution radiation hybrid mapping resolved the gene order as cen-PPY-HOXB6-NGFR-GIP-NME1-tel. GIP maps distal to NGFR with an estimated distance of 250 kb.

Original language	English (US)
Pages (from-to)	589-591
Number of pages	3
Journal	Genomics
Volume	19
Issue number	3
DOIs	https://doi.org/10.1006/geno.1994.1114
State	Published - Feb 1994

ASJC Scopus subject areas

Genetics

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abstract = "Glucose-dependent insulinotropic polypeptide (GIP) has been regionally localized to a gene cluster on human chromosome 17q. Genetic mapping through CEPH reference families demonstrated that GIP was tightly linked to NME1 and PPY and fully linked to HOXB6 and NGFR. High-resolution radiation hybrid mapping resolved the gene order as cen-PPY-HOXB6-NGFR-GIP-NME1-tel. GIP maps distal to NGFR with an estimated distance of 250 kb.",

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AU - Lewis, T. B.

AU - Saenz, M.

AU - O’Connell, P.

AU - Leach, R. J.

PY - 1994/2

Y1 - 1994/2

N2 - Glucose-dependent insulinotropic polypeptide (GIP) has been regionally localized to a gene cluster on human chromosome 17q. Genetic mapping through CEPH reference families demonstrated that GIP was tightly linked to NME1 and PPY and fully linked to HOXB6 and NGFR. High-resolution radiation hybrid mapping resolved the gene order as cen-PPY-HOXB6-NGFR-GIP-NME1-tel. GIP maps distal to NGFR with an estimated distance of 250 kb.

AB - Glucose-dependent insulinotropic polypeptide (GIP) has been regionally localized to a gene cluster on human chromosome 17q. Genetic mapping through CEPH reference families demonstrated that GIP was tightly linked to NME1 and PPY and fully linked to HOXB6 and NGFR. High-resolution radiation hybrid mapping resolved the gene order as cen-PPY-HOXB6-NGFR-GIP-NME1-tel. GIP maps distal to NGFR with an estimated distance of 250 kb.

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JF - Genomics

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Localization of glucose-dependent insulinotropic polypeptide (GIP) to a gene cluster on chromosome 17q

Abstract

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