Localization of glucose-dependent insulinotropic polypeptide (GIP) to a gene cluster on chromosome 17q

T. B. Lewis, M. Saenz, P. O’Connell, R. J. Leach

Research output: Contribution to journalArticle

6 Scopus citations

Abstract

Glucose-dependent insulinotropic polypeptide (GIP) has been regionally localized to a gene cluster on human chromosome 17q. Genetic mapping through CEPH reference families demonstrated that GIP was tightly linked to NME1 and PPY and fully linked to HOXB6 and NGFR. High-resolution radiation hybrid mapping resolved the gene order as cen-PPY-HOXB6-NGFR-GIP-NME1-tel. GIP maps distal to NGFR with an estimated distance of 250 kb.

Original languageEnglish (US)
Pages (from-to)589-591
Number of pages3
JournalGenomics
Volume19
Issue number3
DOIs
StatePublished - Feb 1994

ASJC Scopus subject areas

  • Genetics

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