Lithium Toxicity and PRES: A Novel Association

Ryan T. Fitzgerald; Caris T. Fitzgerald; Rohan S. Samant; Manoj Kumar; Raghu Ramakrishniah; Rudy Van Hemert; Edgardo J. Angtuaco

doi:10.1111/jon.12094

Lithium Toxicity and PRES: A Novel Association

Ryan T. Fitzgerald
, Caris T. Fitzgerald
, Rohan S. Samant
, Manoj Kumar
, Raghu Ramakrishniah
, Rudy Van Hemert
, Edgardo J. Angtuaco

Research output: Contribution to journal › Article › peer-review

9 Scopus citations

Abstract

We report two cases of posterior reversible encephalopathy syndrome (PRES) occurring in association with supra-therapeutic serum lithium levels. Although the neurologic manifestations of lithium toxicity are well known, this is, to our knowledge, the first report describing a link between lithium toxicity and PRES. We discuss the current understanding of the pathogenesis of PRES and suggest mechanisms by which lithium may play a role in its development.

Original language	English (US)
Pages (from-to)	147-149
Number of pages	3
Journal	Journal of Neuroimaging
Volume	25
Issue number	1
DOIs	https://doi.org/10.1111/jon.12094
State	Published - Jan 1 2015
Externally published	Yes

Keywords

Hypertensive encephalopathy
Lithium
Posterior reversible encephalopathy syndrome
Seizure

ASJC Scopus subject areas

Radiology Nuclear Medicine and imaging
Clinical Neurology

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10.1111/jon.12094

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title = "Lithium Toxicity and PRES: A Novel Association",

abstract = "We report two cases of posterior reversible encephalopathy syndrome (PRES) occurring in association with supra-therapeutic serum lithium levels. Although the neurologic manifestations of lithium toxicity are well known, this is, to our knowledge, the first report describing a link between lithium toxicity and PRES. We discuss the current understanding of the pathogenesis of PRES and suggest mechanisms by which lithium may play a role in its development.",

keywords = "Hypertensive encephalopathy, Lithium, Posterior reversible encephalopathy syndrome, Seizure",

author = "Fitzgerald, \{Ryan T.\} and Fitzgerald, \{Caris T.\} and Samant, \{Rohan S.\} and Manoj Kumar and Raghu Ramakrishniah and \{Van Hemert\}, Rudy and Angtuaco, \{Edgardo J.\}",

note = "Publisher Copyright: {\textcopyright} 2014 by the American Society of Neuroimaging.",

year = "2015",

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doi = "10.1111/jon.12094",

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T1 - Lithium Toxicity and PRES

T2 - A Novel Association

AU - Fitzgerald, Ryan T.

AU - Fitzgerald, Caris T.

AU - Samant, Rohan S.

AU - Kumar, Manoj

AU - Ramakrishniah, Raghu

AU - Van Hemert, Rudy

AU - Angtuaco, Edgardo J.

PY - 2015/1/1

Y1 - 2015/1/1

N2 - We report two cases of posterior reversible encephalopathy syndrome (PRES) occurring in association with supra-therapeutic serum lithium levels. Although the neurologic manifestations of lithium toxicity are well known, this is, to our knowledge, the first report describing a link between lithium toxicity and PRES. We discuss the current understanding of the pathogenesis of PRES and suggest mechanisms by which lithium may play a role in its development.

AB - We report two cases of posterior reversible encephalopathy syndrome (PRES) occurring in association with supra-therapeutic serum lithium levels. Although the neurologic manifestations of lithium toxicity are well known, this is, to our knowledge, the first report describing a link between lithium toxicity and PRES. We discuss the current understanding of the pathogenesis of PRES and suggest mechanisms by which lithium may play a role in its development.

KW - Hypertensive encephalopathy

KW - Lithium

KW - Posterior reversible encephalopathy syndrome

KW - Seizure

UR - https://www.scopus.com/pages/publications/84920945854

UR - https://www.scopus.com/pages/publications/84920945854#tab=citedBy

U2 - 10.1111/jon.12094

DO - 10.1111/jon.12094

M3 - Article

C2 - 24571251

AN - SCOPUS:84920945854

SN - 1051-2284

VL - 25

SP - 147

EP - 149

JO - Journal of Neuroimaging

JF - Journal of Neuroimaging

IS - 1

ER -

Lithium Toxicity and PRES: A Novel Association

Abstract

Keywords

ASJC Scopus subject areas

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