Lithium carbonate absorption in humans

E. T. Sugita, J. W. Stokes, Alan Frazer, P. Grof, J. Mendels, F. J. Goldstein, P. J. Niebergall

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

Plasma levels and urinary excretion of lithium using lithium carbonate capsules from two manufacturers were correlated with the in vitro dissolution results. Tests indicated that the dissolution rates differed markedly for the two different capsules. It was also found that the absorption patterns of the capsules were different; one exhibited rapid initial absorption resulting in high peak levels, while the other showed a slower, more prolonged pattern. However, the extent of absorption of lithium was identical for the two preparations.

Original languageEnglish (US)
Pages (from-to)264-270
Number of pages7
JournalJournal of Clinical Pharmacology
Volume13
Issue number7
StatePublished - 1973
Externally publishedYes

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Lithium Carbonate
Capsules
Lithium

ASJC Scopus subject areas

  • Pharmacology (medical)
  • Pharmacology, Toxicology and Pharmaceutics(all)

Cite this

Sugita, E. T., Stokes, J. W., Frazer, A., Grof, P., Mendels, J., Goldstein, F. J., & Niebergall, P. J. (1973). Lithium carbonate absorption in humans. Journal of Clinical Pharmacology, 13(7), 264-270.

Lithium carbonate absorption in humans. / Sugita, E. T.; Stokes, J. W.; Frazer, Alan; Grof, P.; Mendels, J.; Goldstein, F. J.; Niebergall, P. J.

In: Journal of Clinical Pharmacology, Vol. 13, No. 7, 1973, p. 264-270.

Research output: Contribution to journalArticle

Sugita, ET, Stokes, JW, Frazer, A, Grof, P, Mendels, J, Goldstein, FJ & Niebergall, PJ 1973, 'Lithium carbonate absorption in humans', Journal of Clinical Pharmacology, vol. 13, no. 7, pp. 264-270.
Sugita ET, Stokes JW, Frazer A, Grof P, Mendels J, Goldstein FJ et al. Lithium carbonate absorption in humans. Journal of Clinical Pharmacology. 1973;13(7):264-270.
Sugita, E. T. ; Stokes, J. W. ; Frazer, Alan ; Grof, P. ; Mendels, J. ; Goldstein, F. J. ; Niebergall, P. J. / Lithium carbonate absorption in humans. In: Journal of Clinical Pharmacology. 1973 ; Vol. 13, No. 7. pp. 264-270.
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