Liposomal Amphotericin B as Monotherapy in Relapsed Coccidioidal Meningitis

Ethan R. Stewart; Matthew L. Eldridge; Ian McHardy; Stuart H. Cohen; George R. Thompson

doi:10.1007/s11046-017-0240-7

Liposomal Amphotericin B as Monotherapy in Relapsed Coccidioidal Meningitis

Ethan R. Stewart, Matthew L. Eldridge, Ian McHardy, Stuart H. Cohen, George R. Thompson

Research output: Contribution to journal › Article › peer-review

6 Scopus citations

Abstract

Coccidioidal meningitis remains a difficult clinical problem, and despite life-long therapy with triazole antifungals, relapses of disease and medication intolerance occur necessitating salvage treatment. We report two patients with recurrent coccidioidal meningitis who improved following a 2-week course of liposomal amphotericin B monotherapy and discuss potential advantages of this treatment option.

Original language	English (US)
Pages (from-to)	619-622
Number of pages	4
Journal	Mycopathologia
Volume	183
Issue number	3
DOIs	https://doi.org/10.1007/s11046-017-0240-7
State	Published - Jun 1 2018
Externally published	Yes

Keywords

Coccidioides
Coccidioidomycosis
Liposomal amphotericin B
Meningitis
Relapse

ASJC Scopus subject areas

Microbiology
Applied Microbiology and Biotechnology
Agronomy and Crop Science
veterinary (miscalleneous)

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10.1007/s11046-017-0240-7

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title = "Liposomal Amphotericin B as Monotherapy in Relapsed Coccidioidal Meningitis",

abstract = "Coccidioidal meningitis remains a difficult clinical problem, and despite life-long therapy with triazole antifungals, relapses of disease and medication intolerance occur necessitating salvage treatment. We report two patients with recurrent coccidioidal meningitis who improved following a 2-week course of liposomal amphotericin B monotherapy and discuss potential advantages of this treatment option.",

keywords = "Coccidioides, Coccidioidomycosis, Liposomal amphotericin B, Meningitis, Relapse",

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AU - Stewart, Ethan R.

AU - Eldridge, Matthew L.

AU - McHardy, Ian

AU - Cohen, Stuart H.

AU - Thompson, George R.

PY - 2018/6/1

Y1 - 2018/6/1

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AB - Coccidioidal meningitis remains a difficult clinical problem, and despite life-long therapy with triazole antifungals, relapses of disease and medication intolerance occur necessitating salvage treatment. We report two patients with recurrent coccidioidal meningitis who improved following a 2-week course of liposomal amphotericin B monotherapy and discuss potential advantages of this treatment option.

KW - Coccidioides

KW - Coccidioidomycosis

KW - Liposomal amphotericin B

KW - Meningitis

KW - Relapse

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Liposomal Amphotericin B as Monotherapy in Relapsed Coccidioidal Meningitis

Abstract

Keywords

ASJC Scopus subject areas

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