Linkage heterogeneity between the C3 and LDLR and the APOA4 and APOA1 loci in baboons

Candace M. Kammerer, James E. Hixson, Mary Jo Aivaliotis, Patricia A. Porter, John L. VandeBerg

    Research output: Contribution to journalArticlepeer-review

    5 Scopus citations

    Abstract

    We detected linkage in baboons between loci for the third component of complement (C3) and the low-density lipoprotein receptor (LDLR), lod score = 5.53, and loci for apolipoprotein A1 (APOA1) and apolipoprotein AIV (APOA4), lod score = 14.59. We also found evidence for linkage heterogeneity among the baboon pedigrees between LDLR and C3 (P = 0.04) and between APOA1 and APOA4 (P = 0.01).

    Original languageEnglish (US)
    Pages (from-to)43-48
    Number of pages6
    JournalGenomics
    Volume14
    Issue number1
    DOIs
    StatePublished - Sep 1992

    ASJC Scopus subject areas

    • Genetics

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