Linkage heterogeneity between the C3 and LDLR and the APOA4 and APOA1 loci in baboons

Candace M. Kammerer, James E. Hixson, Mary Jo Aivaliotis, Patricia A. Porter, John L. VandeBerg

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    Abstract

    We detected linkage in baboons between loci for the third component of complement (C3) and the low-density lipoprotein receptor (LDLR), lod score = 5.53, and loci for apolipoprotein A1 (APOA1) and apolipoprotein AIV (APOA4), lod score = 14.59. We also found evidence for linkage heterogeneity among the baboon pedigrees between LDLR and C3 (P = 0.04) and between APOA1 and APOA4 (P = 0.01).

    Original languageEnglish (US)
    Pages (from-to)43-48
    Number of pages6
    JournalGenomics
    Volume14
    Issue number1
    DOIs
    Publication statusPublished - Sep 1992

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    ASJC Scopus subject areas

    • Genetics

    Cite this

    Kammerer, C. M., Hixson, J. E., Aivaliotis, M. J., Porter, P. A., & VandeBerg, J. L. (1992). Linkage heterogeneity between the C3 and LDLR and the APOA4 and APOA1 loci in baboons. Genomics, 14(1), 43-48. https://doi.org/10.1016/S0888-7543(05)80281-2