Abstract
We performed a total of 12 gastric emptying studies on 6 normal subjects with a hyperosmolar (1.85 mol/l) 400-kcal glucose solution commonly used for diagnosing diabetes and a more dilute (0.62 mol/l) 200-kcal glucose solution. The gastric half-emptying time was greatly prolonged with both glucose solutions; 107 min for the (1.85 mol/l) 400-kcal glucose solution compared to 66 min for the more dilute (0.62 mol/l) 200-kcal glucose solution. Although the 200-kcal glucose solution contained one-half the amount of glucose (50 g) compared to the 400-kcal solution (100 g), the blood glucose values obtained during a 2-hr period were only slightly lower with the former solution. This study demonstrates significantly delayed gastric emptying of glucose solutions in normal subjects and a linear pattern of gastric emptying formerly associated only with solid meals.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 377-381 |
| Number of pages | 5 |
| Journal | Journal of Nuclear Medicine |
| Volume | 32 |
| Issue number | 3 |
| State | Published - 1991 |
Fingerprint
ASJC Scopus subject areas
- Radiological and Ultrasound Technology
Cite this
Linear gastric emptying of hyperosmolar glucose solutions. / Phillips, William T; Schwartz, J. G.; Blumhardt, R.; McMahan, C. A.
In: Journal of Nuclear Medicine, Vol. 32, No. 3, 1991, p. 377-381.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Linear gastric emptying of hyperosmolar glucose solutions
AU - Phillips, William T
AU - Schwartz, J. G.
AU - Blumhardt, R.
AU - McMahan, C. A.
PY - 1991
Y1 - 1991
N2 - We performed a total of 12 gastric emptying studies on 6 normal subjects with a hyperosmolar (1.85 mol/l) 400-kcal glucose solution commonly used for diagnosing diabetes and a more dilute (0.62 mol/l) 200-kcal glucose solution. The gastric half-emptying time was greatly prolonged with both glucose solutions; 107 min for the (1.85 mol/l) 400-kcal glucose solution compared to 66 min for the more dilute (0.62 mol/l) 200-kcal glucose solution. Although the 200-kcal glucose solution contained one-half the amount of glucose (50 g) compared to the 400-kcal solution (100 g), the blood glucose values obtained during a 2-hr period were only slightly lower with the former solution. This study demonstrates significantly delayed gastric emptying of glucose solutions in normal subjects and a linear pattern of gastric emptying formerly associated only with solid meals.
AB - We performed a total of 12 gastric emptying studies on 6 normal subjects with a hyperosmolar (1.85 mol/l) 400-kcal glucose solution commonly used for diagnosing diabetes and a more dilute (0.62 mol/l) 200-kcal glucose solution. The gastric half-emptying time was greatly prolonged with both glucose solutions; 107 min for the (1.85 mol/l) 400-kcal glucose solution compared to 66 min for the more dilute (0.62 mol/l) 200-kcal glucose solution. Although the 200-kcal glucose solution contained one-half the amount of glucose (50 g) compared to the 400-kcal solution (100 g), the blood glucose values obtained during a 2-hr period were only slightly lower with the former solution. This study demonstrates significantly delayed gastric emptying of glucose solutions in normal subjects and a linear pattern of gastric emptying formerly associated only with solid meals.
UR - http://www.scopus.com/inward/record.url?scp=0025969945&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0025969945&partnerID=8YFLogxK
M3 - Article
C2 - 2005444
AN - SCOPUS:0025969945
VL - 32
SP - 377
EP - 381
JO - Journal of Nuclear Medicine
JF - Journal of Nuclear Medicine
SN - 0161-5505
IS - 3
ER -