Linear gastric emptying of hyperosmolar glucose solutions

William T Phillips, J. G. Schwartz, R. Blumhardt, C. A. McMahan

Research output: Contribution to journalArticle

29 Citations (Scopus)

Abstract

We performed a total of 12 gastric emptying studies on 6 normal subjects with a hyperosmolar (1.85 mol/l) 400-kcal glucose solution commonly used for diagnosing diabetes and a more dilute (0.62 mol/l) 200-kcal glucose solution. The gastric half-emptying time was greatly prolonged with both glucose solutions; 107 min for the (1.85 mol/l) 400-kcal glucose solution compared to 66 min for the more dilute (0.62 mol/l) 200-kcal glucose solution. Although the 200-kcal glucose solution contained one-half the amount of glucose (50 g) compared to the 400-kcal solution (100 g), the blood glucose values obtained during a 2-hr period were only slightly lower with the former solution. This study demonstrates significantly delayed gastric emptying of glucose solutions in normal subjects and a linear pattern of gastric emptying formerly associated only with solid meals.

Original languageEnglish (US)
Pages (from-to)377-381
Number of pages5
JournalJournal of Nuclear Medicine
Volume32
Issue number3
StatePublished - 1991

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Gastric Emptying
Glucose
Meals
Blood Glucose

ASJC Scopus subject areas

  • Radiological and Ultrasound Technology

Cite this

Phillips, W. T., Schwartz, J. G., Blumhardt, R., & McMahan, C. A. (1991). Linear gastric emptying of hyperosmolar glucose solutions. Journal of Nuclear Medicine, 32(3), 377-381.

Linear gastric emptying of hyperosmolar glucose solutions. / Phillips, William T; Schwartz, J. G.; Blumhardt, R.; McMahan, C. A.

In: Journal of Nuclear Medicine, Vol. 32, No. 3, 1991, p. 377-381.

Research output: Contribution to journalArticle

Phillips, WT, Schwartz, JG, Blumhardt, R & McMahan, CA 1991, 'Linear gastric emptying of hyperosmolar glucose solutions', Journal of Nuclear Medicine, vol. 32, no. 3, pp. 377-381.
Phillips WT, Schwartz JG, Blumhardt R, McMahan CA. Linear gastric emptying of hyperosmolar glucose solutions. Journal of Nuclear Medicine. 1991;32(3):377-381.
Phillips, William T ; Schwartz, J. G. ; Blumhardt, R. ; McMahan, C. A. / Linear gastric emptying of hyperosmolar glucose solutions. In: Journal of Nuclear Medicine. 1991 ; Vol. 32, No. 3. pp. 377-381.
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