Light, timing of biological rhythms, and chronodisruption in man

Thomas C. Erren, Russel J Reiter, Claus Piekarski

Research output: Contribution to journalArticle

70 Citations (Scopus)

Abstract

This paper reviews abundant evidence suggesting that causes and course of aging and cancers can be considered as being both light- and rhythm-related. We define chronodisruption as a relevant disturbance of orderly biological rhythms over days and seasons and years in man. Light is the primary external mediator and melatonin a primary internal intermediary of such disturbances, which can result in earlier deaths via premature aging and cancers. We conclude that experimental and epidemiological research can provide further insights into common denominators of these chronic processes and may offer novel and uniform targets for prevention.

Original languageEnglish (US)
Pages (from-to)485-494
Number of pages10
JournalNaturwissenschaften
Volume90
Issue number11
DOIs
StatePublished - Nov 2003

Fingerprint

biological rhythm
biological rhythms
Periodicity
cancer
Aging of materials
Premature Aging
Light
disturbance
neoplasms
melatonin
Melatonin
Neoplasms
death
Research

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • Ecology

Cite this

Light, timing of biological rhythms, and chronodisruption in man. / Erren, Thomas C.; Reiter, Russel J; Piekarski, Claus.

In: Naturwissenschaften, Vol. 90, No. 11, 11.2003, p. 485-494.

Research output: Contribution to journalArticle

Erren, Thomas C. ; Reiter, Russel J ; Piekarski, Claus. / Light, timing of biological rhythms, and chronodisruption in man. In: Naturwissenschaften. 2003 ; Vol. 90, No. 11. pp. 485-494.
@article{a634162cbae74635b4b0d121936528d8,
title = "Light, timing of biological rhythms, and chronodisruption in man",
abstract = "This paper reviews abundant evidence suggesting that causes and course of aging and cancers can be considered as being both light- and rhythm-related. We define chronodisruption as a relevant disturbance of orderly biological rhythms over days and seasons and years in man. Light is the primary external mediator and melatonin a primary internal intermediary of such disturbances, which can result in earlier deaths via premature aging and cancers. We conclude that experimental and epidemiological research can provide further insights into common denominators of these chronic processes and may offer novel and uniform targets for prevention.",
author = "Erren, {Thomas C.} and Reiter, {Russel J} and Claus Piekarski",
year = "2003",
month = "11",
doi = "10.1007/s00114-003-0468-6",
language = "English (US)",
volume = "90",
pages = "485--494",
journal = "Die Naturwissenschaften",
issn = "0028-1042",
publisher = "Springer Verlag",
number = "11",

}

TY - JOUR

T1 - Light, timing of biological rhythms, and chronodisruption in man

AU - Erren, Thomas C.

AU - Reiter, Russel J

AU - Piekarski, Claus

PY - 2003/11

Y1 - 2003/11

N2 - This paper reviews abundant evidence suggesting that causes and course of aging and cancers can be considered as being both light- and rhythm-related. We define chronodisruption as a relevant disturbance of orderly biological rhythms over days and seasons and years in man. Light is the primary external mediator and melatonin a primary internal intermediary of such disturbances, which can result in earlier deaths via premature aging and cancers. We conclude that experimental and epidemiological research can provide further insights into common denominators of these chronic processes and may offer novel and uniform targets for prevention.

AB - This paper reviews abundant evidence suggesting that causes and course of aging and cancers can be considered as being both light- and rhythm-related. We define chronodisruption as a relevant disturbance of orderly biological rhythms over days and seasons and years in man. Light is the primary external mediator and melatonin a primary internal intermediary of such disturbances, which can result in earlier deaths via premature aging and cancers. We conclude that experimental and epidemiological research can provide further insights into common denominators of these chronic processes and may offer novel and uniform targets for prevention.

UR - http://www.scopus.com/inward/record.url?scp=0344944174&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0344944174&partnerID=8YFLogxK

U2 - 10.1007/s00114-003-0468-6

DO - 10.1007/s00114-003-0468-6

M3 - Article

VL - 90

SP - 485

EP - 494

JO - Die Naturwissenschaften

JF - Die Naturwissenschaften

SN - 0028-1042

IS - 11

ER -