Left ventricular hypertrophy in acute stroke patients with known hypertension

Askiel Bruno, Desiree D. Brooks, Taryn A. Abrams, Mitra D. Poorak, Drew Gunio, Prianka K. Kandhal, Aleena Lakhanpal, Arun K. Nagabandi, Abiodun E. Akinwuntan, Stephen Looney, Pascha E. Schafer

Research output: Contribution to journalArticlepeer-review

9 Scopus citations


Background: Despite effective treatments, hypertension remains uncontrolled in nearly half of the people with hypertension in the United States. Uncontrolled hypertension leads to end organ damage, such as left ventricular hypertrophy (LVH). To identify reasons for uncontrolled hypertension, we interviewed acute stroke patients with a history of hypertension and evaluated for LVH. Methods: Using a standardized questionnaire, we collected demographic, socioeconomic, and health-care data in 300 acute ischemic and hemorrhagic stroke patients in one hospital. We also collected relevant clinical data from medical records. We analyzed factors associated with echocardiographic LVH as a marker of uncontrolled hypertension in 190 acute stroke patients with a history of hypertension. Results: Overall, 46% (88/190) of patients had LVH. In univariate analysis, lower household income and self-reported poor adherence to hypertension treatment were significantly associated with increased risk of LVH. In multiple logit modeling, only poor adherence to hypertension treatment remained significantly associated with LVH, odds ratio 1.77 (95% CI: 1.01–3.11), p < 0.05. Conclusions: In acute stroke patients, poor adherence to hypertension treatment is a significant independent predictor of LVH. A clear reason for poor adherence to treatment is elusive in a large proportion of these patients in our study. Further research is needed to identify and develop strategies to combat the key factors responsible for poor adherence to hypertension treatment.

Original languageEnglish (US)
Pages (from-to)502-504
Number of pages3
JournalClinical and Experimental Hypertension
Issue number6
StatePublished - Aug 18 2017
Externally publishedYes


  • African American
  • body mass index
  • hypertension
  • left ventricular hypertrophy
  • stroke

ASJC Scopus subject areas

  • Internal Medicine
  • Physiology


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