Left inferior parietal lobe engagement in social cognition and language

Danilo Bzdok, Gesa Hartwigsen, Andrew Reid, Angela R. Laird, Peter T. Fox, Simon B. Eickhoff

Research output: Contribution to journalReview article

49 Scopus citations

Abstract

Social cognition and language are two core features of the human species. Despite distributed recruitment of brain regions in each mental capacity, the left parietal lobe (LPL) represents a zone of topographical convergence. The present study quantitatively summarizes hundreds of neuroimaging studies on social cognition and language. Using connectivity-based parcellation on a meta-analytically defined volume of interest (VOI), regional coactivation patterns within this VOI allowed identifying distinct subregions. Across parcellation solutions, two clusters emerged consistently in rostro-ventral and caudo-ventral aspects of the parietal VOI. Both clusters were functionally significantly associated with social-cognitive and language processing. In particular, the rostro-ventral cluster was associated with lower-level processing facets, while the caudo-ventral cluster was associated with higher-level processing facets in both mental capacities. Contrarily, in the (less stable) dorsal parietal VOI, all clusters reflected computation of general-purpose processes, such as working memory and matching tasks, that are frequently co-recruited by social or language processes. Our results hence favour a rostro-caudal distinction of lower- versus higher-level processes underlying social cognition and language in the left inferior parietal lobe.

Original languageEnglish (US)
Pages (from-to)319-334
Number of pages16
JournalNeuroscience and Biobehavioral Reviews
Volume68
DOIs
StatePublished - Sep 1 2016

Keywords

  • Connectivity-based parcellation
  • Functional connectivity
  • Functional decoding
  • Speech
  • Statistical learning
  • Theory of mind

ASJC Scopus subject areas

  • Neuropsychology and Physiological Psychology
  • Cognitive Neuroscience
  • Behavioral Neuroscience

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