Lateral Ridge Augmentation and Implant Placement: An Experimental Study Evaluating Implant Osseointegration in Different Augmentation Materials in the Canine Mandible

Thomas Von Arx, David L. Cochran, Joachim S. Hermann, Robert K. Schenk, Frank L. Higginbottom, Daniel Buser

Research output: Contribution to journalArticle

86 Scopus citations


The present study investigated the osseointegration of dental implants with a titanium plasma-sprayed surface (TPS) in regenerated and native bone in an experimental dog study. Initially, lateral bone defects were created in the alveolar ridge on both sides of the mandible. Two months later, lateral ridge augmentation was performed with (1) autogenous corticocancellous block grafts, (2) autogenous corticocancellous block grafts and e-PTFE membrane, (3) tricalcium phosphate particles and e-PTFE membrane, or (4) canine-derived demineralized freeze-dried bone allograft particles and e-PTFE membrane. After 4 months, membranes were removed, and non-submerged titanium implants were placed in regenerated bone (test implants) and in native bone (control implants). Two months later, the animals were sacrificed and non-decalcified orofacial sections were evaluated histometrically. All implants demonstrated high percentages (59% to 75%) of bone-to-implant contact, with no significant differences across the various treatment groups. The different grafting techniques did not significantly influence the location of first bone-to-implant contact and the horizontal bone width at the most coronal bone level.

Original languageEnglish (US)
Pages (from-to)343-354
Number of pages12
JournalInternational Journal of Oral and Maxillofacial Implants
Issue number3
StatePublished - Dec 1 2001



  • Autogenous bone
  • Barrier membrane
  • Demineralized freeze-dried bone allograft
  • Histometry
  • Osseointegration
  • Ridge augmentation
  • Titanium implant
  • Tricalcium phosphate

ASJC Scopus subject areas

  • Oral Surgery

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