Latent intracellular Epstein-Barr virus DNA demonstrated in ocular posttransplant lymphoproliferative disorder mimicking granulomatous uveitis with iris nodules in a child

Mary O'Hara; William C. Lloyd; Frank W. Scribbick; Margaret L. Gulley

doi:10.1067/mpa.2001.112444

Latent intracellular Epstein-Barr virus DNA demonstrated in ocular posttransplant lymphoproliferative disorder mimicking granulomatous uveitis with iris nodules in a child

Mary O'Hara, William C. Lloyd, Frank W. Scribbick, Margaret L. Gulley

Department of Ophthalmology

Research output: Contribution to journal › Article › peer-review

10 Scopus citations

Abstract

A case of intraocular posttransplant lymphoproliferative disorder (PTLD) is described in a 9-year-old female who underwent orthotopic liver transplantation at the age of 18 months. The prevalence of ophthalmic involvement in PTLD can be expected to rise with the increasing number of major organ transplantations, as well as improved survivorship. Children are particularly at risk for this posttransplant complication because they are usually seronegative for the Epstein-Barr virus (EBV) prior to transplant. Accurate diagnostic classification of PTLD to include confirmation of EBV infection carries significant therapeutic and prognostic implications.

Original language	English (US)
Pages (from-to)	62-63
Number of pages	2
Journal	Journal of AAPOS
Volume	5
Issue number	1
DOIs	https://doi.org/10.1067/mpa.2001.112444
State	Published - Feb 2001

ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health
Ophthalmology

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abstract = "A case of intraocular posttransplant lymphoproliferative disorder (PTLD) is described in a 9-year-old female who underwent orthotopic liver transplantation at the age of 18 months. The prevalence of ophthalmic involvement in PTLD can be expected to rise with the increasing number of major organ transplantations, as well as improved survivorship. Children are particularly at risk for this posttransplant complication because they are usually seronegative for the Epstein-Barr virus (EBV) prior to transplant. Accurate diagnostic classification of PTLD to include confirmation of EBV infection carries significant therapeutic and prognostic implications.",

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AU - Gulley, Margaret L.

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AB - A case of intraocular posttransplant lymphoproliferative disorder (PTLD) is described in a 9-year-old female who underwent orthotopic liver transplantation at the age of 18 months. The prevalence of ophthalmic involvement in PTLD can be expected to rise with the increasing number of major organ transplantations, as well as improved survivorship. Children are particularly at risk for this posttransplant complication because they are usually seronegative for the Epstein-Barr virus (EBV) prior to transplant. Accurate diagnostic classification of PTLD to include confirmation of EBV infection carries significant therapeutic and prognostic implications.

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Latent intracellular Epstein-Barr virus DNA demonstrated in ocular posttransplant lymphoproliferative disorder mimicking granulomatous uveitis with iris nodules in a child

Abstract

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