Late-onset temporal lobe epilepsy in a patient with juvenile myoclonic epilepsy

Octavian V. Lie, Mark D. Holmes

Research output: Contribution to journalComment/debatepeer-review

1 Scopus citations


We report a patient with longstanding, severe juvenile myoclonic epilepsy who subsequently developed features of temporal lobe epilepsy, which gradually became clinically dominant. Over the years, there was an electrographic evolution from the typical generalised epileptiform patterns, characteristic of juvenile myoclonic epilepsy, to the novel appearance of interictal temporal spikes immediately preceding bisynchronous discharges, and subsequently to temporal intermittent rhythmic delta activity and temporal lobe-onset seizures. In this rare case of coexistent primary generalised epilepsy and focal epilepsy, the epileptic networks of the two forms of epilepsy appear to overlap.

Original languageEnglish (US)
Pages (from-to)190-194
Number of pages5
JournalEpileptic Disorders
Issue number2
StatePublished - Jun 2012


  • Coexistence
  • JME
  • Juvenile myoclonic epilepsy
  • TLE
  • Temporal

ASJC Scopus subject areas

  • Clinical Neurology
  • Neurology


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