Late-developing cerebral arteropathy after pyogenic meningitis

Santiago Palacio, Robert G. Hart, Dennis G. Vollmer, Kathleen Kagan-Hallet

Research output: Contribution to journalArticlepeer-review

25 Scopus citations


Background: Although vasculopathy is a recognized complication during acute meningitis, to our knowledge, no previous reports have been published of this phenomenon developing months after successful treatment. Objective: To report a unique case of a late-developing vasculopathy after pyogenic meningitis in an adult. Report of a Case: A 51-year-old woman was seen with severe headache 2 months after treatment of Haemophilus influenzae type C meningitis. Initial arteriography showed no abnormality; a second arteriogram showed progressive multifocal intracranial stenosis affecting mainly the internal carotid arteries. Findings from pathologic examination disclosed diffuse collagenosis consistent with chronic vascular injury from meningitis. The arterial lesions stabilized, and the patient remained asymptomatic. Conclusion: Progressive intracranial arterial stenosis can evolve months after meningitis and should be added to the list of recognized vascular complications.

Original languageEnglish (US)
Pages (from-to)431-433
Number of pages3
JournalArchives of Neurology
Issue number3
StatePublished - Mar 1 2003

ASJC Scopus subject areas

  • Arts and Humanities (miscellaneous)
  • Clinical Neurology


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