Laser angioplasty using a lensed-fiber delivery system and a pulsed Nd-YAG laser. Early clinical results

Christopher J. White, Stephen R. Ramee, Juan E. Mesa, Larry H. Hollier, Joseph P. Murgo, Michael Aita, Gene Samson, Maureen Godfrey

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

We performed a clinical trial to evaluate the safety and efficacy of a unique lensed-fiber delivery system with a pulsed Neodymium-yttrium aluminum garnet (Nd-YAG) laser in patients with atherosclerotic peripheral vascular disease. The lensed-fiber consists of a spherical silica lens, 1.5 mm in diameter, mounted at the distal tip of a 300 μm silica optical fiber. The Nd-YAG laser is pulsed at 10 Hz, and we delivered 0.5 J/pulse with a pulse duration of 100 msecs in 2- to 5-second bursts. Successful recanalization of stenoses or occlusions was obtained in 9 of 10 patients and was manifested by improvement in blood flow as measured angiographically and with ankle-brachial blood pressure index improvement (> 0.15). There were no arterial perforations or dissections associated with the laser angioplasty. All successfully recanalized patients required adjunctive balloon angioplasty to obtain a satisfactory reduction in luminal diameter stenosis of the treated artery. We conclude that this unique delivery system and the pulsed Nd-YAG laser are a safe and effective method of recanalizing arterial stenoses not amendable to conventional balloon angioplasty alone.

Original languageEnglish (US)
Title of host publicationProceedings of SPIE - The International Society for Optical Engineering
EditorsAbraham Katzir
PublisherPubl by Int Soc for Optical Engineering
Pages206-210
Number of pages5
ISBN (Print)0819402427
StatePublished - Dec 1 1990
EventProceedings of Optical Fibers in Medicine V - Los Angeles, CA, USA
Duration: Jan 14 1990Jan 19 1990

Publication series

NameProceedings of SPIE - The International Society for Optical Engineering
Volume1201
ISSN (Print)0277-786X

Other

OtherProceedings of Optical Fibers in Medicine V
CityLos Angeles, CA, USA
Period1/14/901/19/90

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ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Condensed Matter Physics
  • Computer Science Applications
  • Applied Mathematics
  • Electrical and Electronic Engineering

Cite this

White, C. J., Ramee, S. R., Mesa, J. E., Hollier, L. H., Murgo, J. P., Aita, M., Samson, G., & Godfrey, M. (1990). Laser angioplasty using a lensed-fiber delivery system and a pulsed Nd-YAG laser. Early clinical results. In A. Katzir (Ed.), Proceedings of SPIE - The International Society for Optical Engineering (pp. 206-210). (Proceedings of SPIE - The International Society for Optical Engineering; Vol. 1201). Publ by Int Soc for Optical Engineering.