@inproceedings{af054b03b697495c9ca07b5914278250,
title = "Laser angioplasty using a lensed-fiber delivery system and a pulsed Nd-YAG laser. Early clinical results",
abstract = "We performed a clinical trial to evaluate the safety and efficacy of a unique lensed-fiber delivery system with a pulsed Neodymium-yttrium aluminum garnet (Nd-YAG) laser in patients with atherosclerotic peripheral vascular disease. The lensed-fiber consists of a spherical silica lens, 1.5 mm in diameter, mounted at the distal tip of a 300 μm silica optical fiber. The Nd-YAG laser is pulsed at 10 Hz, and we delivered 0.5 J/pulse with a pulse duration of 100 msecs in 2- to 5-second bursts. Successful recanalization of stenoses or occlusions was obtained in 9 of 10 patients and was manifested by improvement in blood flow as measured angiographically and with ankle-brachial blood pressure index improvement (> 0.15). There were no arterial perforations or dissections associated with the laser angioplasty. All successfully recanalized patients required adjunctive balloon angioplasty to obtain a satisfactory reduction in luminal diameter stenosis of the treated artery. We conclude that this unique delivery system and the pulsed Nd-YAG laser are a safe and effective method of recanalizing arterial stenoses not amendable to conventional balloon angioplasty alone.",
author = "White, {Christopher J.} and Ramee, {Stephen R.} and Mesa, {Juan E.} and Hollier, {Larry H.} and Murgo, {Joseph P.} and Michael Aita and Gene Samson and Maureen Godfrey",
year = "1990",
doi = "10.1117/12.17538",
language = "English (US)",
isbn = "0819402427",
series = "Proceedings of SPIE - The International Society for Optical Engineering",
publisher = "Publ by Int Soc for Optical Engineering",
pages = "206--210",
booktitle = "Proceedings of SPIE - The International Society for Optical Engineering",
note = "Proceedings of Optical Fibers in Medicine V ; Conference date: 14-01-1990 Through 19-01-1990",
}