Lambert-eaton myasthenic syndrome and merkel cell carcinoma

Nam D. Nguyen, Daniel B. Simmons, Adrian R. Bersabe, Thomas M. Duginski, John H. Sladky, Douglas Walton, Micah Will, John S. Renshaw

Research output: Contribution to journalArticlepeer-review

Abstract

Lambert-Eaton myasthenic syndrome (LEMS) is an antibodymediated disorder of the neuromuscular junction that is most commonly diagnosed in association with small cell lung carcinoma (SCLC). Small cell lung carcinoma is histologically similar to the aggressive cutaneous neuroendocrine malignancy Merkel cell carcinoma (MCC). We provide a full report and longitudinal clinical follow-up of a case of LEMS occurring with MCC. We also review the literature on paraneoplastic syndromes associated with MCC and other nonpulmonary small cell carcinomas.

Original languageEnglish (US)
Pages (from-to)E19-E23
JournalCutis
Volume103
Issue number5
StatePublished - Jan 1 2019
Externally publishedYes

ASJC Scopus subject areas

  • Dermatology

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