The interrelationship between the rat pineal, ovary, and hypophysis was examined utilizing organ weight, histology, RNA content, and RNA:DNA ratio as an index of synthetic activity. Six weeks post-pinealectomy, no change in ovarian function was observed utilizing the above parameters. A time-dependent action of pinealectomy on ovarian activity is postulated. Following ovariectomy a significant increase in pineal weight was seen. This suggests the existence of a feedback mechanism between the pineal and anterior pituitary similar to that of other endocrine organs.
|Original language||English (US)|
|Number of pages||4|
|Journal||Proceedings of the Society for Experimental Biology and Medicine|
|State||Published - Dec 1971|
ASJC Scopus subject areas
- Biochemistry, Genetics and Molecular Biology(all)