Lack of cerebrospinal fluid myelin basic protein in HIV- infected asymptomatic individuals with intrathecal synthesis of IgG

Douglas W. Marshall, Robin L. Brey

Research output: Contribution to journalArticle

7 Scopus citations

Abstract

We evaluated 130 consecutive HIV-infected neurologically aeymptomatic hdividuals for intrathecal IgG production and myelin basic protein (MBP) levels. Although 56.7% of immunologically normal and 68.8% of immuno-compromised patients had some CSF abnormality, no patient had an abnormal MBP level. The lack of MBP elevation in the CSF of these patients suggests that the production of intrathecal IgG is not related to active demyelination.

Original languageEnglish (US)
Pages (from-to)1127-1129
Number of pages3
JournalNeurology
Volume39
Issue number8
StatePublished - Aug 1989
Externally publishedYes

ASJC Scopus subject areas

  • Clinical Neurology

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