We evaluated 130 consecutive HIV-infected neurologically aeymptomatic hdividuals for intrathecal IgG production and myelin basic protein (MBP) levels. Although 56.7% of immunologically normal and 68.8% of immuno-compromised patients had some CSF abnormality, no patient had an abnormal MBP level. The lack of MBP elevation in the CSF of these patients suggests that the production of intrathecal IgG is not related to active demyelination.
ASJC Scopus subject areas
- Clinical Neurology