Karyometric studies of thyroid follicular cells and thyroid hormone secretion in the male Syrian hamsters following melatonin and diazepam administration

E. Sewerynek, A. Lewinski, S. M. Webb, M. K. Vaughan, R. J. Reiter

Research output: Contribution to journalArticle

1 Scopus citations

Abstract

We observed a decreasing effect of late-afternoon melatonin (Mel) injections [but not subcutaneously (s.c.) implanted Mel pellets] on the volume of nuclei of thyroid follicular cells (TFC) in male Syrian hamsters. That effect was reversed by diazepam (DZ), chronically released from s.c. implanted pellets. Diazepam, both in injections and in pellets, tended to increase the volume of TFC nuclei, but that rise did not attain statistical significance. On the other hand, DZ, neither in injections nor in pellets, did influence the concentration of thyroid hormones in any significant way.

Original languageEnglish (US)
Pages (from-to)393-400
Number of pages8
JournalNeuroendocrinology Letters
Volume13
Issue number6
StatePublished - Dec 1 1991
Externally publishedYes

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism
  • Endocrinology
  • Neurology
  • Endocrine and Autonomic Systems
  • Clinical Neurology
  • Psychiatry and Mental health

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