Isolation of swinholide A and related glycosylated derivatives from two field collections of marine cyanobacteria

Eric H. Andrianasolo, Harald Gross, Douglas Goeger, Mirjam Musafija-Girt, Kerry McPhail, Rachel M. Leal, Susan L. Mooberry, William H. Gerwick

Research output: Contribution to journalArticlepeer-review

86 Scopus citations

Abstract

(Chemical Equation Presented) Chemical investigation of two field collections of marine cyanobacteria has led to the discovery of two new cytotoxic natural products, ankaraholides A (2) and B (3), along with the known compound swinholide A (1). Since swinholide-type compounds were previously localized to the heterotrophic bacteria of sponges, these findings raise intriguing questions about their true metabolic source.

Original languageEnglish (US)
Pages (from-to)1375-1378
Number of pages4
JournalOrganic Letters
Volume7
Issue number7
DOIs
StatePublished - Mar 31 2005
Externally publishedYes

ASJC Scopus subject areas

  • Biochemistry
  • Physical and Theoretical Chemistry
  • Organic Chemistry

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