Isolation and characterization of Mycoplasma genitalium strains from the human respiratory tract

J. B. Baseman, S. F. Dallo, J. G. Tully, D. L. Rose

Research output: Contribution to journalArticle

97 Citations (Scopus)

Abstract

Mycoplasma genitalium, an organism first isolated from the urethras of two men with nongonococcal urethritis, has been found in throat specimens from military recruits participating in an inactivated Mycoplasma pneumoniae vaccine field trial in 1974-1975. Four of 16 preserved throat isolates, previously identified as strains of M. pneumoniae, have now been shown to be mixtures of M. pneumoniae and M. genitalium. Purification of these mixed mycoplasmas by selection of single colonies confirmed the presence of M. genitalium. Identification of M. genitalium was based upon the occurrence of a species-specific 140-kilodalton protein adhesin in these isolates and their serologic reactivity to an M. genitalium antiserum. The frequent occurrence of both M. pneumoniae and M. genitalium in a number of these throat specimens, in combination with their shared antigenic cross-reactivities, suggests the likelihood that M. genitalium strains are easily missed in the usual laboratory identification procedures. What role M. genitalium may play in human respiratory disease remains to be determined.

Original languageEnglish (US)
Pages (from-to)2266-2269
Number of pages4
JournalJournal of Clinical Microbiology
Volume26
Issue number11
StatePublished - 1988

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Mycoplasma genitalium
Respiratory System
Mycoplasma pneumoniae
Pharynx
Urethritis
Mycoplasma
Urethra
Immune Sera
Vaccines

ASJC Scopus subject areas

  • Microbiology
  • Microbiology (medical)

Cite this

Baseman, J. B., Dallo, S. F., Tully, J. G., & Rose, D. L. (1988). Isolation and characterization of Mycoplasma genitalium strains from the human respiratory tract. Journal of Clinical Microbiology, 26(11), 2266-2269.

Isolation and characterization of Mycoplasma genitalium strains from the human respiratory tract. / Baseman, J. B.; Dallo, S. F.; Tully, J. G.; Rose, D. L.

In: Journal of Clinical Microbiology, Vol. 26, No. 11, 1988, p. 2266-2269.

Research output: Contribution to journalArticle

Baseman, JB, Dallo, SF, Tully, JG & Rose, DL 1988, 'Isolation and characterization of Mycoplasma genitalium strains from the human respiratory tract', Journal of Clinical Microbiology, vol. 26, no. 11, pp. 2266-2269.
Baseman, J. B. ; Dallo, S. F. ; Tully, J. G. ; Rose, D. L. / Isolation and characterization of Mycoplasma genitalium strains from the human respiratory tract. In: Journal of Clinical Microbiology. 1988 ; Vol. 26, No. 11. pp. 2266-2269.
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