Isavuconazole in the treatment of coccidioidal meningitis

Arash Heidari, Miriam Quinlan, David J. Benjamin, Brett Laurence, Anandit Mu, Tiffany Ngai, Wes J. Hoffman, Stuart H. Cohen, Ian McHardy, Royce Johnson, George R. Thompson

Research output: Contribution to journalArticlepeer-review

17 Scopus citations


Patients with coccidioidal meningitis require lifelong antifungal therapy. Cumulative toxicity and lack of antifungal efficacy require salvage therapy in the treatment of some patients. In a retrospective review of nine patients with coccidioidal meningitis treated with isavuconazole, successful therapy was seen in three patients and stable disease was confirmed in six patients. Isavuconazole may be a useful addition to the therapeutic choices currently available for coccidioidal meningitis.

Original languageEnglish (US)
Article numbere02232-18
JournalAntimicrobial agents and chemotherapy
Issue number3
StatePublished - Mar 2019
Externally publishedYes


  • Coccidioides
  • Isavuconazole
  • Meningitis

ASJC Scopus subject areas

  • Pharmacology
  • Pharmacology (medical)
  • Infectious Diseases


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