Is there an association between systemic lupus erythematosus and periodontal disease?

Débora Cerqueira Calderaro, Gilda Aparecida Ferreira, Santuza Maria Souza de Mendonça, Jôice Dias Corrêa, Fabrícia Xavier Santos, João Guilherme Capinam Sanção, Tarcília Aparecida da Silva, Antônio Lúcio Teixeira

Research output: Contribution to journalArticlepeer-review

13 Scopus citations


Periodontal disease results from the interaction between pathogenic bacteria that colonizesupragingival and subgingival biofilms and the host, triggering an inflammatory response, with systemic effects leading to immune-mediated destruction of the attachment appara-tus and loss of supporting alveolar bone. Immunological pathways and predisposing geneticfactors common to periodontal disease and rheumatic diseases, including systemic lupuserythematosus, have been described. Case reports have suggested greater severity of peri-odontal disease in patients with systemic lupus erythematosus. However, studies evaluatingthe influence of the treatment of one disease on the clinical and laboratory manifestationsof the other have yielded conflicting results.

Original languageEnglish (US)
Pages (from-to)280-284
Number of pages5
JournalRevista Brasileira de Reumatologia
Issue number3
StatePublished - 2016
Externally publishedYes


  • Chronic periodontitis
  • Periodontitis
  • Systemic lupus erythematosus

ASJC Scopus subject areas

  • Rheumatology


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