Is patient outcome compromised during the initial experience with robot-assisted radical cystectomy? Results of 164 consecutive cases

Matthew H. Hayn, Nicholas J. Hellenthal, Stéfanie A. Seixas-Mikelus, Ahmed M. Mansour, Andrew Stegemann, Abid Hussain, Khurshid A. Guru

Research output: Contribution to journalArticlepeer-review

51 Scopus citations

Abstract

OBJECTIVE Robot-assisted radical cystectomy (RARC) remains controversial in terms of oncologic outcomes, especially during the initial experience. The purpose of this study was to evaluate the impact of initial experience of robotic cystectomy programs on oncologic outcomes and overall survival. PATIENTS AND METHODS Utilizing a prospectively maintained, single institution robotic cystectomy database, we identified 164 consecutive patients who underwent RARC since November 2005. After stratification by age group, gender, pathologic T stage, lymph node status, surgical margin status, and sequential case number; we used chi-squared analyses to correlate sequential case number to operative time, surgical blood loss, lymph node yield, and surgical margin status. We also addressed the relationship between complications and sequential case number. We then utilized Cox proportional hazard modeling and Kaplan-Meier survival analyses to correlate variables to overall mortality. RESULTS Sequential case number was not significantly associated with increased incidence of complications, surgical blood loss, or positive surgical margins (P= 0.780, P= 0.548, P= 0.545). Case number was, however, significantly associated with shorter operative time and mean number of lymph nodes retrieved (P < 0.001, P < 0.001). Sequential case number was not significantly associated with survival; however, tumour stage, the presence of lymph node metastases, and positive surgical margins were significantly associated with death. Although being the largest of its kind, this was a small study with short follow-up when compared to open cystectomy series. CONCLUSION Initial experience with RARC did not affect the incidence of positive surgical margins, operative/postoperative complications, or overall survival in a single-institution series.

Original languageEnglish (US)
Pages (from-to)882-887
Number of pages6
JournalBJU International
Volume108
Issue number6
DOIs
StatePublished - Sep 2011
Externally publishedYes

Keywords

  • bladder cancer
  • learning curve
  • radical cystectomy
  • robot-assisted

ASJC Scopus subject areas

  • Urology

Fingerprint Dive into the research topics of 'Is patient outcome compromised during the initial experience with robot-assisted radical cystectomy? Results of 164 consecutive cases'. Together they form a unique fingerprint.

Cite this