Irrigation in Regenerative Endodontic Procedures

Research output: Chapter in Book/Report/Conference proceedingChapter


The developing dentition is at risk for pulpal necrosis due to trauma and developmental dental anomalies such as dens evaginatus. Loss of an immature permanent tooth in young patients with mixed dentition can be devastating, leading to loss of function, malocclusion, and inadequate maxillofacial development. These teeth traditionally have been treated with apexification procedures using either long-term calcium hydroxide treatment or immediate placement of a mineral trioxide aggregate (MTA) apical plug. Although these treatments often result in the resolution of signs and symptoms of pathosis, they provide little to no benefit for continued root development. Thus, immature teeth treated with these procedures are considered in a state of “arrested development,” and no further root growth, normal pulpal nociception, and immune defense should be expected.

Original languageEnglish (US)
Title of host publicationEndodontic Irrigation
Subtitle of host publicationChemical Disinfection of the Root Canal System
PublisherSpringer International Publishing
Number of pages12
ISBN (Electronic)9783319164564
ISBN (Print)9783319164557
StatePublished - Jan 1 2015


  • Chemical debridement
  • Dentin matrix
  • Irrigation
  • Regenerative endodontic procedure
  • Regenerative endodontic procedures
  • Residual intracanal medicaments

ASJC Scopus subject areas

  • General Dentistry


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