Involvement of cytochrome b-245 in the respiratory burst of human neutrophils

N. Borregaard, E. R. Simons, R. A. Clark

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Abstract

The cytochrome b-245 of human neutrophils was reduced when the neutrophils under anaerobic conditions were stimulated by serum-treated zymosan, immune complexes, or phorbol myristate acetate. Reintroduction of oxygen rapidly reoxidized the cytochrome; azide was without effect on any of these reactions. This indicates that cytochrome b-245 participates in the respiratory burst of neutrophils.

Original languageEnglish (US)
Pages (from-to)1301-1303
Number of pages3
JournalInfection and Immunity
Volume38
Issue number3
StatePublished - Dec 1 1982

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ASJC Scopus subject areas

  • Parasitology
  • Microbiology
  • Immunology
  • Infectious Diseases

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