The cytochrome b-245 of human neutrophils was reduced when the neutrophils under anaerobic conditions were stimulated by serum-treated zymosan, immune complexes, or phorbol myristate acetate. Reintroduction of oxygen rapidly reoxidized the cytochrome; azide was without effect on any of these reactions. This indicates that cytochrome b-245 participates in the respiratory burst of neutrophils.
ASJC Scopus subject areas
- Infectious Diseases