Abstract
Bovine chondrocytes were seeded on glass slides which are coated with bovine serum albumin and fibronectin for comparison. Following cell attachment for 24 hours, the attachment forces of bovine chondrocyte were measured using the newly designed cytodetachment apparatus. By manipulating the microscope stage and the instrument's six-degree-of-freedom assembly, the cytodetachment probe approaches the attached cell from its side. It was found that adhesion of cells to the foreign surface is a necessary prerequisite to facilitate focal adhesions and cell proliferation. Furthermore, the changes in cell adhesiveness that were observed is due to the intrinsic properties of cells, as modulated by different substrates.
| Original language | English (US) |
|---|---|
| Title of host publication | Southern Biomedical Engineering Conference - Proceedings |
| Place of Publication | Piscataway, NJ, United States |
| Publisher | IEEE |
| Pages | 61 |
| Number of pages | 1 |
| State | Published - 1998 |
| Event | Proceedings of the 1998 17th Southern Biomedical Engineering Conference - San Antonio, TX, USA Duration: Feb 6 1998 → Feb 8 1998 |
Other
| Other | Proceedings of the 1998 17th Southern Biomedical Engineering Conference |
|---|---|
| City | San Antonio, TX, USA |
| Period | 2/6/98 → 2/8/98 |
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ASJC Scopus subject areas
- Engineering(all)
Cite this
Investigation of cellular adhesiveness as a function of substrate using cytodetachment technique. / Athanasiou, K. A.; Shin, D.; Thoma, B.; Agrawal, C. M.; Lebaron, R. G.
Southern Biomedical Engineering Conference - Proceedings. Piscataway, NJ, United States : IEEE, 1998. p. 61.Research output: Chapter in Book/Report/Conference proceeding › Conference contribution
}
TY - GEN
T1 - Investigation of cellular adhesiveness as a function of substrate using cytodetachment technique
AU - Athanasiou, K. A.
AU - Shin, D.
AU - Thoma, B.
AU - Agrawal, C. M.
AU - Lebaron, R. G.
PY - 1998
Y1 - 1998
N2 - Bovine chondrocytes were seeded on glass slides which are coated with bovine serum albumin and fibronectin for comparison. Following cell attachment for 24 hours, the attachment forces of bovine chondrocyte were measured using the newly designed cytodetachment apparatus. By manipulating the microscope stage and the instrument's six-degree-of-freedom assembly, the cytodetachment probe approaches the attached cell from its side. It was found that adhesion of cells to the foreign surface is a necessary prerequisite to facilitate focal adhesions and cell proliferation. Furthermore, the changes in cell adhesiveness that were observed is due to the intrinsic properties of cells, as modulated by different substrates.
AB - Bovine chondrocytes were seeded on glass slides which are coated with bovine serum albumin and fibronectin for comparison. Following cell attachment for 24 hours, the attachment forces of bovine chondrocyte were measured using the newly designed cytodetachment apparatus. By manipulating the microscope stage and the instrument's six-degree-of-freedom assembly, the cytodetachment probe approaches the attached cell from its side. It was found that adhesion of cells to the foreign surface is a necessary prerequisite to facilitate focal adhesions and cell proliferation. Furthermore, the changes in cell adhesiveness that were observed is due to the intrinsic properties of cells, as modulated by different substrates.
UR - http://www.scopus.com/inward/record.url?scp=0031650567&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0031650567&partnerID=8YFLogxK
M3 - Conference contribution
AN - SCOPUS:0031650567
SP - 61
BT - Southern Biomedical Engineering Conference - Proceedings
PB - IEEE
CY - Piscataway, NJ, United States
ER -