Abstract
Bovine chondrocytes were seeded on glass slides which are coated with bovine serum albumin and fibronectin for comparison. Following cell attachment for 24 hours, the attachment forces of bovine chondrocyte were measured using the newly designed cytodetachment apparatus. By manipulating the microscope stage and the instrument's six-degree-of-freedom assembly, the cytodetachment probe approaches the attached cell from its side. It was found that adhesion of cells to the foreign surface is a necessary prerequisite to facilitate focal adhesions and cell proliferation. Furthermore, the changes in cell adhesiveness that were observed is due to the intrinsic properties of cells, as modulated by different substrates.
| Original language | English (US) |
|---|---|
| Number of pages | 1 |
| State | Published - Jan 1 1998 |
| Event | Proceedings of the 1998 17th Southern Biomedical Engineering Conference - San Antonio, TX, USA Duration: Feb 6 1998 → Feb 8 1998 |
Other
| Other | Proceedings of the 1998 17th Southern Biomedical Engineering Conference |
|---|---|
| City | San Antonio, TX, USA |
| Period | 2/6/98 → 2/8/98 |
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ASJC Scopus subject areas
- Engineering(all)
Cite this
Athanasiou, K. A., Shin, D., Thoma, B., Agrawal, C. M., & Lebaron, R. G. (1998). Investigation of cellular adhesiveness as a function of substrate using cytodetachment technique. Paper presented at Proceedings of the 1998 17th Southern Biomedical Engineering Conference, San Antonio, TX, USA, .