Investigating brain dynamics and connectivity with functional MRI

Eugene Duff, Gary Egan, Ross Cunnington, Iven Mareels, Binquan Wang, Peter Fox, Jinhu Xiong

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

Functional Magnetic Resonance Imaging (fMRI) scans provide a record of ongoing neural processing through the measurement of changes in regional levels of blood oxygenation. While subjects are resting, fMRI has revealed networks of brain regions exhibiting synchronised 0.02 - 0.12 Hz fluctuations in spontaneous, low frequency brain activity. The physiology underlying these 'resting state' fluctuations is poorly understood. Our current research investigates these networks within the human motor system, assessing their persistence over time, their covariance structure, and the effects that motor performance and training have on the networks. Here we present a review of this study, focusing on the methods involved in assessing the fMRI data, discussing issues of region identification, signal extraction, signal to noise, network covariance analysis and the detection of changes in the networks.

Original languageEnglish (US)
Title of host publicationProceedings of the 2004 Intelligent Sensors, Sensor Networks and Information Processing Conference, ISSNIP '04
EditorsM. Palaniswami, B. Krishnamachari, A. Sowmya, S. Challa, M. Palaniswami, B. Krishnamachari, A. Sowmya, S. Challa
Pages565-570
Number of pages6
StatePublished - Dec 1 2004
Externally publishedYes
Event2004 Intelligent Sensors, Sensor Networks and Information Processing Conference, ISSNIP '04 - Melbourne, Australia
Duration: Dec 14 2004Dec 17 2004

Publication series

NameProceedings of the 2004 Intelligent Sensors, Sensor Networks and Information Processing Conference, ISSNIP '04

Other

Other2004 Intelligent Sensors, Sensor Networks and Information Processing Conference, ISSNIP '04
CountryAustralia
CityMelbourne
Period12/14/0412/17/04

ASJC Scopus subject areas

  • Engineering(all)

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  • Cite this

    Duff, E., Egan, G., Cunnington, R., Mareels, I., Wang, B., Fox, P., & Xiong, J. (2004). Investigating brain dynamics and connectivity with functional MRI. In M. Palaniswami, B. Krishnamachari, A. Sowmya, S. Challa, M. Palaniswami, B. Krishnamachari, A. Sowmya, & S. Challa (Eds.), Proceedings of the 2004 Intelligent Sensors, Sensor Networks and Information Processing Conference, ISSNIP '04 (pp. 565-570). (Proceedings of the 2004 Intelligent Sensors, Sensor Networks and Information Processing Conference, ISSNIP '04).