Invasive fungal sinusitis and meningitis due to Arthrographis kalrae in a patient with AIDS

P. V. Chin-Hong, D. A. Sutton, M. Roemer, M. A. Jacobson, J. A. Aberg

Research output: Contribution to journalArticlepeer-review

25 Scopus citations

Abstract

We report the first described case of Arthrographis kalrae pansinusitis and meningitis in a patient with AIDS. The patient was initially diagnosed with Arthrographis kalrae pansinusitis by endoscopic biopsy and culture. The patient was treated with itraconazole for approximately 5 months and then died secondary to Pneumocytis carinii pneumonia. Postmortem examination revealed invasive fungal sinusitis that involved the sphenoid sinus and that extended through the cribiform plate into the inferior surfaces of the bilateral frontal lobes. There was also an associated fungal meningitis and vasculitis with fungal thrombosis and multiple recent infarcts that involved the frontal lobes, right caudate nucleus, and putamen. Post mortem cultures were positive for A. kalrae.

Original languageEnglish (US)
Pages (from-to)804-807
Number of pages4
JournalJournal of clinical microbiology
Volume39
Issue number2
DOIs
StatePublished - 2001

ASJC Scopus subject areas

  • Microbiology (medical)

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