Abstract
Colchicine, a drug used for centuries in the treatment of gout, has been reported to be effective for low-back pain due to disc disorders. A prospective, randomized, double-blind study evaluating the therapeutic effect of intravenous colchicine was conducted in a group of patients with low-back pain with symptoms originating less an 6 months previously. Each patient completed a questionnaire and a pain drawing. Laboratory studies including uric acid and sedimentation rate were performed, as was a detailed physical examination and lumbar thermography. All treatment parameters (including physical therapy, anti-inflammatory medications, and instructions) were constant except that each patient received either intravenous colchicine or intravenous saline. Results indicate a significant difference between the two groups, the intravenous colchicine group showing improvement in symptoms for a few hours or days over a 3-week course of treatment. However, the relief was often of short duration.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 716-717 |
| Number of pages | 2 |
| Journal | Spine |
| Volume | 15 |
| Issue number | 7 |
| DOIs | |
| State | Published - 1990 |
| Externally published | Yes |
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Keywords
- intravenous colchicine
- low-back pain
- prospective study
- therapeutic response
ASJC Scopus subject areas
- Physiology
- Clinical Neurology
- Orthopedics and Sports Medicine
Cite this
Intravenous colchicine for low-back pain : A double-blind study. / Simmons, J. W.; Harris, W. P.; Koulisis, C. W.; Kimmich, S. J.
In: Spine, Vol. 15, No. 7, 1990, p. 716-717.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Intravenous colchicine for low-back pain
T2 - A double-blind study
AU - Simmons, J. W.
AU - Harris, W. P.
AU - Koulisis, C. W.
AU - Kimmich, S. J.
PY - 1990
Y1 - 1990
N2 - Colchicine, a drug used for centuries in the treatment of gout, has been reported to be effective for low-back pain due to disc disorders. A prospective, randomized, double-blind study evaluating the therapeutic effect of intravenous colchicine was conducted in a group of patients with low-back pain with symptoms originating less an 6 months previously. Each patient completed a questionnaire and a pain drawing. Laboratory studies including uric acid and sedimentation rate were performed, as was a detailed physical examination and lumbar thermography. All treatment parameters (including physical therapy, anti-inflammatory medications, and instructions) were constant except that each patient received either intravenous colchicine or intravenous saline. Results indicate a significant difference between the two groups, the intravenous colchicine group showing improvement in symptoms for a few hours or days over a 3-week course of treatment. However, the relief was often of short duration.
AB - Colchicine, a drug used for centuries in the treatment of gout, has been reported to be effective for low-back pain due to disc disorders. A prospective, randomized, double-blind study evaluating the therapeutic effect of intravenous colchicine was conducted in a group of patients with low-back pain with symptoms originating less an 6 months previously. Each patient completed a questionnaire and a pain drawing. Laboratory studies including uric acid and sedimentation rate were performed, as was a detailed physical examination and lumbar thermography. All treatment parameters (including physical therapy, anti-inflammatory medications, and instructions) were constant except that each patient received either intravenous colchicine or intravenous saline. Results indicate a significant difference between the two groups, the intravenous colchicine group showing improvement in symptoms for a few hours or days over a 3-week course of treatment. However, the relief was often of short duration.
KW - intravenous colchicine
KW - low-back pain
KW - prospective study
KW - therapeutic response
UR - http://www.scopus.com/inward/record.url?scp=0024995559&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0024995559&partnerID=8YFLogxK
U2 - 10.1097/00007632-199007000-00018
DO - 10.1097/00007632-199007000-00018
M3 - Article
C2 - 2145645
AN - SCOPUS:0024995559
VL - 15
SP - 716
EP - 717
JO - Spine
JF - Spine
SN - 0362-2436
IS - 7
ER -