Intraoperative evaluation of margin status: How much is enough?

Kenneth N. Holder, I. Tien Yeh

Research output: Contribution to journalReview articlepeer-review

7 Scopus citations


Frozen section examination of the surgical margin status is commonly requested by surgeons during cancer resections. Intraoperative evaluation helps ensure that the tumor is completely excised and can improve local control and patient survival. The accuracy of frozen section analysis is improved with knowledge of diagnostic pitfalls and interpretive challenges. A case report of a head and neck carcinoma is discussed, and recommendations for methodology and interpretation of margin status are outlined for relevant organ systems.

Original languageEnglish (US)
Pages (from-to)148-155
Number of pages8
JournalPathology Case Reviews
Issue number5
StatePublished - Sep 2010


  • frozen section
  • margins

ASJC Scopus subject areas

  • Pathology and Forensic Medicine


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