Intraoperative autologous transfusion of hemolyzed blood

Tod B. Sloan, Greg Myers, Daniel J. Janik, Evalina M. Burger, Vikas V. Patel, Leslie C. Jameson

Research output: Contribution to journalArticlepeer-review

9 Scopus citations

Abstract

During two cases of lumbar spine surgery with instrumentation, we used intraoperative autologous transfusion (IAT), resulting in hemolysis during collection and hemoglobinuria and coagulation abnormalities after transfusion. Hemolysis during IAT collection can lead to hemoglobinuria and binding of nitric oxide, leading to vasoconstriction. The literature suggests that stroma from damaged cells and contact of the blood with the IAT device can lead to coagulation abnormalities and other morbidities, including adult respiratory distress syndrome.

Original languageEnglish (US)
Pages (from-to)38-42
Number of pages5
JournalAnesthesia and analgesia
Volume109
Issue number1
DOIs
StatePublished - Jul 2009
Externally publishedYes

ASJC Scopus subject areas

  • Anesthesiology and Pain Medicine

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