Intraoperative autologous transfusion of hemolyzed blood

Tod B. Sloan; Greg Myers; Daniel J. Janik; Evalina M. Burger; Vikas V. Patel; Leslie C. Jameson

doi:10.1213/ane.0b013e3181a335e4

Intraoperative autologous transfusion of hemolyzed blood

Tod B. Sloan, Greg Myers, Daniel J. Janik, Evalina M. Burger, Vikas V. Patel, Leslie C. Jameson

Research output: Contribution to journal › Article › peer-review

9 Scopus citations

Abstract

During two cases of lumbar spine surgery with instrumentation, we used intraoperative autologous transfusion (IAT), resulting in hemolysis during collection and hemoglobinuria and coagulation abnormalities after transfusion. Hemolysis during IAT collection can lead to hemoglobinuria and binding of nitric oxide, leading to vasoconstriction. The literature suggests that stroma from damaged cells and contact of the blood with the IAT device can lead to coagulation abnormalities and other morbidities, including adult respiratory distress syndrome.

Original language	English (US)
Pages (from-to)	38-42
Number of pages	5
Journal	Anesthesia and analgesia
Volume	109
Issue number	1
DOIs	https://doi.org/10.1213/ane.0b013e3181a335e4
State	Published - Jul 2009
Externally published	Yes

ASJC Scopus subject areas

Anesthesiology and Pain Medicine

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10.1213/ane.0b013e3181a335e4

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AU - Myers, Greg

AU - Janik, Daniel J.

AU - Burger, Evalina M.

AU - Patel, Vikas V.

AU - Jameson, Leslie C.

PY - 2009/7

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AB - During two cases of lumbar spine surgery with instrumentation, we used intraoperative autologous transfusion (IAT), resulting in hemolysis during collection and hemoglobinuria and coagulation abnormalities after transfusion. Hemolysis during IAT collection can lead to hemoglobinuria and binding of nitric oxide, leading to vasoconstriction. The literature suggests that stroma from damaged cells and contact of the blood with the IAT device can lead to coagulation abnormalities and other morbidities, including adult respiratory distress syndrome.

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Intraoperative autologous transfusion of hemolyzed blood

Abstract

ASJC Scopus subject areas

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