Abstract
Intracranial aneurysm is a cerebrovascular disease characterized by local pathological enlargement of cerebral arteries. Many risk factors are involved in the pathogenesis, but the precise mechanisms underlying formation, progression, and rupture remain unclear. This chapter provides a comprehensive overview of the epidemiology, pathophysiology, classification systems, and diagnostic management based on current evidence in literature. Special regard is dedicated to histological and angioarchitectural features, natural history, rupture predictor signs, and risk stratification for intracranial aneurysms. Clinical characteristics of subarachnoid hemorrhage and the best diagnostic techniques are presented in order to improve patient evaluation and choice of successful treatment strategy.
| Original language | English (US) |
|---|---|
| Title of host publication | Neurovascular Surgical Diseases |
| Subtitle of host publication | a Case-Based Approach |
| Publisher | Nova Science Publisher Inc. |
| Pages | 81-106 |
| Number of pages | 26 |
| ISBN (Electronic) | 9781536182644 |
| State | Published - Jan 1 2020 |
| Externally published | Yes |
Keywords
- Endothelial disfunction
- Inflammation
- Intracranial aneurysm
- Subarachnoid hemorrhage
- Wall shear stress
ASJC Scopus subject areas
- General Medicine